Publications pertaining to liver diseases

024.  Mumby, S.M. and B.D. Hammock. 1979. Substrate selectivity and stereochemistry of enzymatic epoxide hydration in the soluble fraction of mouse liver. Pestic. Biochem. Physiol. 11:275-284. https://ucdavis.box.com/s/gpall5cbvn9kalwujbr9cjbeai169ufv 

 

026.  Gill, S.S. and B.D. Hammock. 1979. Hydration of cis- and trans-epoxymethyl stearates by the cytosolic epoxide hydrase of mouse liver. Biochem. Biophys. Res. Commun. 89(3):965-971.  https://ucdavis.box.com/s/w1geevnlnf9c3wkd6i0n5t2wjoavo108  

 

031.  Hammock, B.D., S.S. Gill, S.M. Mumby and K. Ota. 1980. Comparison of epoxide hydrases in the soluble and microsomal fractions of mammalian liver. In: Molecular Basis of Environmental Toxicity, (Bhatnagar, R.S., ed.), pp. 229-272, Ann Arbor Science Publishers, Ann Arbor, Michigan. https://ucdavis.box.com/s/3m5n06ssq30jcrfi32td7vwdqh19d7hz  

 

033.  Ota, K. and B.D. Hammock. 1980. Cytosolic and microsomal epoxide hydrolases: differential properties in mammalian liver. Science. 207:1479-1481. https://ucdavis.box.com/s/u3ovyb9azmbj9whirwadopynhiraru4p  

 

035.  El-Tantawy, M.A. and B.D. Hammock. 1980. The effect of hepatic microsomal and cytosolic subcellular fractions on the mutagenic activity of epoxide-containing compounds in the Salmonella assay. Mutat. Res. 79:59-71. https://ucdavis.box.com/s/e86lk32uiceixgripgv0v30titymg5d7  

 

039.  Hammock, B.D., M. Ratcliff and D.A. Schooley. 1980. Hydration of an 180 epoxide by a cytosolic epoxide hydrolase from mouse liver. Life Sci. 27:1635-1641. https://ucdavis.box.com/s/o1q047uwi60ohj6o8mwrtlg7viwhuv36  

 

043.  Gill, S.S. and B.D. Hammock. 1981. Epoxide hydrolase activity in the mitochondrial fraction of mouse liver. Nature. 291(5811):167-168.  https://ucdavis.box.com/s/ih3hrijqzbp7rc5dkecz31uwtninbe6d  

 

048.  Gill, S.S. and B.D. Hammock. 1981. Epoxide hydrolase activity in the mitochondrial and submitochondrial fractions of mouse liver. Biochem. Pharmacol. 30(15):2111-2120. https://ucdavis.box.com/s/z9tsqjnltt8ssvo842wm6p9xe0qv5xd6  

 

063.  Hammock, B.D. and L.S. Hasagawa.  1983.  Differential substrate selectivity of murine hepatic cytosolic and microsomal epoxide hydrolases.  Biochem. Pharmacol.  32(7):1155-1164. https://ucdavis.box.com/s/lkn7bfp0jonk7l0k6hw3lk1e8jinye3q  

 

068.  Gill, S.S., K. Ota, B. Ruebner and B.D. Hammock.  1983.  Microsomal and cytosolic epoxide hydrolases in rhesus monkey liver, and in normal and neoplastic human liver.  Life Sci.  32:2693-2700. https://ucdavis.box.com/s/ubofeq9k4htu1ityyq00p7rntg1nemuy  

 

090.  Moody, D.E., D.N. Loury and B.D. Hammock.  1985.  Epoxide metabolism in the liver of mice treated with clofibrate (ethyl-- (p-chlorophenoxyisobutyrate), a peroxisome proliferator.  Toxicol. Appl. Pharmacol.  78:351-362. https://ucdavis.box.com/s/zutbyjn47exg82nxn9c8qf1x8quzx1pz  

 

098.  Hammock, B.D., G.D. Prestwich, D.N. Loury, P.Y.K. Cheung, W.S. Eng, S.K. Park, D.E. Moody, M.H. Silva and R.N. Wixtrom.  1986.  Comparison of crude and affinity purified cytosolic epoxide hydrolases from hepatic tissue of control and clofibrate-fed mice.  Arch. Biochem. Biophys.  244(1):292-309. https://ucdavis.box.com/s/c0zqmzbl5ss22vzlnrb85104vnntuh00  

 

102.  Moody, D.E., M.H. Silva and B.D. Hammock. 1986. Epoxide hydrolysis in the cytosol of rat liver, kidney, and testis. Measurement in the presence of glutathione and the effect of dietary clofibrate. Biochem Pharmacol. 35(13):2073-2080. PMID: 3015145. https://ucdavis.box.com/s/ubcffy6sslg2rz7x1h5tmhxi4bry7gd7  

 

107.  Helferich, W.G., E.G. Carroad, M.D. Easter, D.E. Moody, B.D. Hammock and L.R. Shull.  1986.  Effect of medroxyprogesterone acetate on hepatic and placental drug metabolism in rats.  Biochem. Pharmacol.  35(20):3655-3658. https://ucdavis.box.com/s/qrz5hjkripsnwd5g2fw12m3pn1rz76sz  

 

109.  Wisniewski, J.A., D.E. Moody, B.D. Hammock and L.R. Shull.  1987.  Interlobular distribution of hepatic xenobiotic-metabolizing enzyme activities in cattle, goats and sheep.  J. Anim. Sci.  64:210-215. https://ucdavis.box.com/s/3yf9g2umsuquekuh4z2p92qhu7lycscy  

 

110.  Gillette, D.M., R.D. Corey, W.G. Helferich, J.M. McFarland, L.J. Lowenstine, D.E. Moody, B.D. Hammock and L.R. Shull.  1987.  Comparative toxicology of tetrachlorobiphenyls in mink and rat.  I.  Changes in hepatic enzyme activity and smooth endoplasmic reticulum volume.  Fundam. Appl. Toxicol.  8:5-14.  https://ucdavis.box.com/s/uxdpr4d9wqob8vs3aj0qv2pattjccvv8  

 

111.  Moody, D.E., D.N. Loury and B.D. Hammock.  1987.  Immunochemical determination of microsomal epoxide hydrolase (preneoplastic antigen) in extrahepatic tissue.  Biochem. Pharmacol.  36(4):570-572.  https://ucdavis.box.com/s/pqq9ogzxc2azfpskvfsnx5jjgbg8xcbc  

 

115.  Silva, M.H. and B.D. Hammock.  1987.  Affinity purification of cytosolic epoxide hydrolase from human, rhesus monkey, baboon, rabbit, rat and mouse liver.  Comp. Biochem. Physiol.  87B(1):95-102.  https://ucdavis.box.com/s/i8egztw20il849ogzwk41u8fx5iggplk  

 

119.  Moody, D.E. and B.D. Hammock.  1987.  The effect of tridiphane (2-(3,5-dichloropohenyl)-2-(2,2,2-trichloroethyl) oxirane) on hepatic epoxide-metabolizing enzymes: Indications of peroxisome proliferation.  Toxicol. Appl. Pharmacol.  89:37-48.  https://ucdavis.box.com/s/dws228bsxd42nauuxfw5vhvnqm6a0lmh  

 

122.  Narloch, B.A., M.P. Lawton, D.E. Moody, B.D. Hammock and L.R. Shull.  1987.  The effects of dicofol on induction of hepatic microsomal metabolism in rats.  Pestic. Biochem. Physiol.  28:362-370. https://ucdavis.box.com/s/3qrf4rwdgo432ud4fdzpin43b74j0zio   

 

125.  Moody, D.E. and B.D. Hammock.  1987.  Purification of microsomal hydrolase from liver of rhesus monkey: Partial separation of cis- and trans-stilbene oxide hydrolase.  Arch. Biochem. Biophys.  258(1):156-166. https://ucdavis.box.com/s/hkw1g7upy4nh2h6m04jiqu7reoae92r7  

 

134.  Magdalou, J. and B.D. Hammock.  1987.  Metabolism of tridiphane (2-(3,5-dichlorophenyl)-2(2,2,2-trichloroethyl) oxirane) by hepatic epoxide hydrolases and glutathione S-transferases in mouse.  Toxicol. Appl. Pharmacol.  91:439-449. https://ucdavis.box.com/s/0xqm043y51palfa2grvme54wedts396q  

 

137.  Moody, D.E., G.A. Clawson, D.A. Geller, L.A. Taylor, J. Button, D.N. Loury, B.D. Hammock and E.A. Smuckler.  1988.  Sodium cholate extraction of rat liver nuclear xenobiotic-metabolizing enzymes.  Biochem. Pharmacol.  37(7):1331-1341. https://ucdavis.box.com/s/rfzfq4s4xktl36iy0b7xl7age9yxld8c  

  

138.  Silva, M.H., R.N. Wixtrom and B.D. Hammock.  1988.  Epoxide-metabolizing enzymes in mammary gland and liver from BALB/c mice and effects of inducers on enzyme activity.  Cancer Res.  48:1390-1397.  https://ucdavis.box.com/s/jdfiwv30v798v63xqcfw35uz2u81z6uh  

 

143.  Magdalou, J. and B.D. Hammock.  1988.  1,2-Epoxycycloalkanes: Substrates and inhibitors of microsomal and cytosolic epoxide hydrolases in mouse liver.  Biochem. Pharmacol.  37(14):2717-2722. https://ucdavis.box.com/s/t42kxovo8pje1ofrfan0dhs00ipphcxh  

 

154.  Moody, D.E., B.D. Hammock, B.H. Ruebner, D.W. Hillman and J.H. Hillman.  1989.  Immunochemical comparison of human and rhesus monkey liver microsomal and the hepatocellular carcinoma-induced human serum epoxide hydrolases (preneoplastic antigens): Basis for an enzyme-linked immunoabsorbent assay.  Carcinogenesis.  10(2):343-349. https://ucdavis.box.com/s/pnd3nrxa85gg3so8b1wazcv2kqw671vm  

 

155.  Lauren, D.J., P.P. Halarnkar, B.D. Hammock and D.E. Hinton. 1989. Microsomal and cytosolic epoxide hydrolase, and glutathione S-transferase activities in the gill, liver, and kidney of the rainbow trout, Salmo gairdneri: Baseline levels and optimization of assay conditions. Biochem Pharmacol. 38(6):881-887.  PMID: 2930590. https://ucdavis.box.com/s/vnqjb3941fll4cskpdbst5srindv2n99  

 

156.  DiBiasio, K.W., M.H. Silva, B.D. Hammock and L.R. Shull.  1989.  Effects of hepatic inducers on testicular epoxide-metabolizing enzymes in the rat and mouse.  Fundam. Appl. Toxicol.  12:449-459. https://ucdavis.box.com/s/y8kq9q8loki1mzfszaa8qgtx2q6jyjfd  

 

162.  Halarnkar, P.P., R.N. Wixtrom, M.H. Silva and B.D. Hammock.  1989.  Catabolism of epoxy fatty esters by the purified epoxide hydrolase from mouse and human liver.  Arch. Biochem. Biophys.  272(1):226-236. https://ucdavis.box.com/s/6to9mbv2bdclo0lfxqdh8ip9dkmlvi5k  

 

192.  Moody, D.E., K.A. Montgomery, M.B.A. Ashour and B.D. Hammock.  1991.  Effects of environmentally encountered epoxides on mouse liver epoxide-metabolizing enzymes.  Biochem. Pharmacol.  41(11):1625-1637. https://ucdavis.box.com/s/h1ww2n6tyjr0r2aiz1brb5vz52ah4h29  

 

205.  Moody, D.E., B.A. Narloch, L.R. Shull and B.D. Hammock.  1991.  The effect of structurally divergent herbicides on mouse liver xenobiotic-metabolizing enzymes (P-450-dependent mono-oxygenases, epoxide hydrolases and glutathione S-transferases) and carnitine acetyltransferase.  Toxicology Letters.  59:175-185. https://ucdavis.box.com/s/9yibjgmjie5xloarh4wojr6vj6j02gr5  

 

219.  Moody, D.E., D.N. Loury, B.D. Hammock, B.H. Ruebner, J.M. Cullen, J.H. Hillman, D.W. Hillman, M.S. Rao, W.T. London, H.-W.L. Hann, I. Millman and M.J. Griffin.  1992.  Serum epoxide hydrolase (preneoplastic antigen) in human and experimental liver injury.  Cancer Epidemiol. Biomarkers & Prevention.  1:395-403. https://ucdavis.box.com/s/nf3wjs1amlbghidqrqhbuqceqzznpzlk    

 

228.  Dietze, E.C., J. Casas, E. Kuwano and B.D. Hammock.  1993.  Inhibition of epoxide hydrolase from human, monkey, bovine, rabbit, and murine liver by trans-3-phenylglycidols.  Comp. Biochem. Physiol.  104B(2):309-314. https://ucdavis.box.com/s/hec8fh3qtup3gcfgfmwcbkl8duw99gh6  

 

231.  Parker, L.M., D.J. Lauren, B.D. Hammock, B. Winder and D.E. Hinton.  1993.  Biochemical and histochemical properties of hepatic tumors of rainbow trout, Oncorhynchus mykiss.  Carcinogenesis.  14(2):211-217. https://ucdavis.box.com/s/54jiuh55kgi9v4nejfje3rs5v1syhdvb  

 

236.  Huang, T.L., S.A. Villalobos and B.D. Hammock.  1993.  Effect of hepatotoxic doses of paracetamol and carbon tetrachloride on the serum and hepatic carboxylesterase activity in mice.  J. Pharm. Pharmacol.  45:458-465. https://ucdavis.box.com/s/hvcwxwg6xwq5bew98rd2akhkjiae5xu2   

 

238.  Huang, T.L., A. Székács, T. Uematsu, E. Kuwano, A. Parkinson and B.D. Hammock.  1993.  Hydrolysis of carbonates, thiocarbonates, carbamates, and carboxylic esters of -naphthol, -naphthol, and p-nitrophenol by human, rat, and mouse liver carboxylesterases.  Pharm. Res.  10(5):639-648. https://ucdavis.box.com/s/m8wn8r2rim6rctwpjpocbfdbvrl3ft5t   

 

240.  Beetham, J.K., T. Tian and B.D. Hammock.  1993.  cDNA cloning and expression of a soluble epoxide hydrolase from human liver  Arch. Biochem. Biophys.  305(1):197-201.  https://ucdavis.box.com/s/vjzsyx4vjxothno4frfm68pa32a6mvvc  

 

241.  Grant, D.F., D.H. Storms and B.D. Hammock.  1993.  Molecular cloning and expression of murine liver soluble epoxide hydrolase.  J. Biol. Chem.  268(23):17628-17633. https://ucdavis.box.com/s/5p4mfk6qc0611nlkbf08k84z5znbvqgv  

 

242.  Winder, B.S., J. Nourooz-Zadeh, R.R. Isseroff, M.F. Moghaddam and B.D. Hammock.  1993.  Properties of enzymes hydrating epoxides in human epidermis and liver.  Int. J. Biochem.  25(9):1291-1301. https://ucdavis.box.com/s/3cluqmu6vabttgblmc5p854l6j2wocyc    

 

278.  Shiotsuki, T., T.L. Huang and B.D. Hammock.  1994.  Affinity purification of mouse liver carboxylesterase with trifluoromethyl ketones as ligands.  J. Pestic. Sci.  19(4):321-324. https://ucdavis.box.com/s/hsb31n5rzqw8e9pywbsxybwm4m1mjj9o      

 

298.  Pinot, F., D.F. Grant, J.L. Spearow, A.G. Parker and B.D. Hammock. 1995. Differential regulation of soluble epoxide hydrolase by clofibrate and sexual hormones in liver and kidneys of mice. Biochem Pharmacol. 50(4):501-508. PMID: 7646556. https://ucdavis.box.com/s/4mvexjp5iwpgreq4eimqm6cqmlvkkwps  

 

328.  Parker, A.G., F. Pinot, D.F. Grant, J. Spearow and B.D. Hammock.  1996.  Regulation of mouse liver microsomal esterases by clofibrate and sexual hormones.  Biochem. Pharmacol.  51(5):677-685. https://ucdavis.box.com/s/4xq56xtkkorcza2n2n8oqjrfxxa1h18q  

 

338.  Zeldin, D.C., C.R. Moomaw, N. Jesse, K.B. Tomer, J. Beetham, B.D. Hammock and S. Wu.  1996.  Biochemical characterization of the human liver cytochrome P450 Arachidonic acid epoxygenase pathway.  Arch. Biochem. Biophys.  330(1):87-96. https://ucdavis.box.com/s/m4wn3wlcjq4l6ehivvd95ra7x9l28u15   

  

347.  Huang, T., T. Shiotsuki, T. Uematsu, B. Borhan, Q. Li and B. Hammock.  1996.  Structure-activity relationships for substrates and inhibitors of mammalian liver microsomal carboxylesterases.  Pharm. Res.  13(10):1495-1500. https://ucdavis.box.com/s/zgnvoswn7y8y0gj9nj4r1i2rvyey2cku  

 

376.  Huang, T.L. and B. D. Hammock. 1997.  Solubilization of mouse liver microsomal carboxylesterases. Pharmaceutical Sciences.  3:605-608. https://ucdavis.box.com/s/55wpboo86zsmtqqsiips2ea6h51ac2vb  

 

411.  Draper, A.J. and B.D. Hammock.  1999.  Soluble epoxide hydrolase in rat inflammatory cells is indistinguishable from soluble epoxide hydrolase in rat liver.  Toxicol. Sci.  50(1):30-35. https://ucdavis.box.com/s/9me245v2syk0u9mh1onnxduuz96gg1zs  

 

415.  Argiriadi, M.A., C. Morisseau, B.D. Hammock and D.W. Christianson.  1999.  Detoxification of environmental mutagens and carcinogens: Structure, mechanism, and evolution of liver epoxide hydrolase.  Proc. Natl. Acad. Sci. USA  96(19):10637-10642. https://ucdavis.box.com/s/pctxgl3wxlt9kr0oghxvc2300abkaw6i  

 

418.  Morisseau, C., M. Derbel, T.R. Lane, D. Stoutamire and B.D. Hammock.  1999.  Differential induction of hepatic drug-metabolizing enzymes by fenvaleric acid in male rats.  Toxicol. Sci. 52(2):148-153. https://ucdavis.box.com/s/re2u2u9zxtd3rmk5ei54c3ss8urmlyal   

 

419. Lakritz J, Winder BS, Noorouz-Zadeh J, Huang TL, Buckpitt AR, Hammock BD, Plopper CG (2000) Hepatic and pulmonary enzyme activities in horses. Am. J. Vet. Res. 61(2):152–157 https://ucdavis.box.com/s/v367jerqxjtakz8su8qmn6qzk9hyzwyd 

 

426.  Draper, A.J. and B.D. Hammock.  2000.  Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase.  Arch. Biochem. Biophys.  376(1):199-205. https://ucdavis.box.com/s/gtkoim9dzvflk40828bfkbj5h6d8m952   

 

472.  Watanabe, T. and B.D. Hammock. 2001 Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high performance liquid chromatography with electrospray tandem mass spectrometry. Anal Biochem. 299:227-234. https://ucdavis.box.com/s/0uhoob4tgaqatct7uspnieg570asoxrs  

 

518.  Wheelock, C.E., Å.M. Karlsson, R. Zhang, J.E. Stok, C. Morisseau, S.E. Le Valley, C.E. Green and B.D. Hammock.  2003.  Evaluation of -cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes.  Anal. Biochem. 315(2):208-222. PMID: 12689831. https://ucdavis.box.com/s/fjdx5tjd8owuhsiosl39up58jx8b6pj9  

 

545.  Stok, J.E., H. Huang, P.D. Jones, C.E. Wheelock, C. Morisseau and B.D. Hammock.  2004.  Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes.  J. Biol. Chem.  279:29863-29869.  PMID: 15123619 https://ucdavis.box.com/s/itufkey0tj22rz9qxu5ie7fg39dl5zkj  

 

588.  Huang, H., C.D. Fleming, K. Nishi, M.R. Redinbo and B.D. Hammock.  2005.  Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases.  Chem. Res. Toxicol.  18(9):1371-1377.  PMID: 16167828. PMCID:PMC 1444893. https://ucdavis.box.com/s/rdcv40s2aljhg2u7yv2ar6u98mko17uf  

 

596.  Nishi, K., H. Huang, S.G. Kamita, I.-H. Kim, C. Morisseau and B.D. Hammock.  2006.  Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2.  Arch. Biochem. Biophys.  445:115-123.  PMID: 16359636. PMCID: PMC1444892. https://ucdavis.box.com/s/3qds52kbi9uxn45kbhgj8kxuc973483r  

 

647.  Wheelock, C.E., S. Goto, B.D. Hammock and J.W. Newman. 2007. Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics.  3(2):137-145. PMID: 19079556. PMCID: PMC2597807. https://ucdavis.box.com/s/f5x593zk24xbe4595ab8qcyhvro1jmdn  

 

703.  Fife, K.L., YM. Liu, K.R. Schmelzer, H-J. Tsai, I-H. Kim, C. Morisseau, B.D. Hammock and D.L. Kroetz. 2008. Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. J. Pharmacol. Exper. Therap. 327(3):707-715. PMCID: PMC2761654. https://ucdavis.box.com/s/vj0k7q4ccgaowof4zk8sri4xrkirhd61  

796. Barhoumi, R., Y. Mouneimne, E. Ramos, C. Morisseau, B.D. Hammock, S. Safe, A.R. Parrish and R.C. Burghardt. 2011.  Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line. Toxicol. Appl. Pharmacol. 253(1):45-56. PMCID: PMC3081912. https://ucdavis.box.com/s/vj0k7q4ccgaowof4zk8sri4xrkirhd61  

 

834. Helferich, W.G., M.H. Silva, W.T. Flueck, B.D. Hammock and L.R. Shull. 1987. Xenobiotic biotransformation in livers and lungs of adult black-tailed deer: comparison with domestic goat and sheep. Comp Biochem Physiol C. 88(1):145-49. PMID: 2890476. https://ucdavis.box.com/s/8k8v292okf869dredbnw955r8h8u5o1r 

 

850. Liu, Y., H.X. Dang, D. Li, W. Pang, B.D. Hammock and Y. Zhu. 2012. Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice. PLoS One. 7(6):e39165. PMID: 22720061. PMCID: PMC3375303. https://ucdavis.box.com/s/myc89f5oft5y25iil7el64va6qm7ykc2 

897. Bettaieb, A., N. Nagata, D. AbouBechara, S. Chahed, C. Morisseau, B.D. Hammock and F.G. Haj. 2013. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. J Biol Chem. 288(20): 14189-99. PMID: 23576437. PMCID: PMC3656275. https://ucdavis.box.com/s/73714n4pv0ksb62hrobxdi7mx5p3jlof  

 

924. Yang, J., P. Solaimani, H. Dong, B.D. Hammock, O. Hankinson. 2013. Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung. J Toxicol Sci. 38(6):833-36. PMID: 24213002. PMCID: PMC4068614. https://ucdavis.box.com/s/adgc104chp37tmu25k1yqvbaxljgfuha  

 

974. Yueh, M.F., K. Taniguchi, S. Chen, R.M. Evans, B.D. Hammock, M. Karin and R.H. Tukey. 2014 Dec. The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proc Natl Acad Sci USA. 111(48):17200-05. PMID: 25404284. PMCID: PMC4260592. https://ucdavis.box.com/s/d9tqpyofmne1azyx9arw1080pd2j49ln  

 

981. Lopez-Vicario, C., V. Garcia-Alonso, J. Alcaraz-Quiles, B. Rius, E. Titos, A. Lopategi, B.D. Hammock, V. Arroyo and J. Claria. 2015 Jan. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver. Role for omega-3 epoxides. Proc Natl Acad Sci USA. 112(2):536-41. PMID: 25550510. PMCID: PMC4299190. https://ucdavis.box.com/s/w8sfsfer7wi3m79z6pq3vdhqlmgcf5x2  

 

991. Harris, T.R., A. Bettaieb, S. Kodani, H. Dong, R. Myers, N. Chiamvimonvat, F.G. Haj and B.D. Hammock. 2015 July. Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice. Toxicol Appl Pharmacol. 286(2):102-111. PMID: 25827057. PMCID: PMC4458210. https://ucdavis.box.com/s/rdc50go3w5aeyabpd2duh337wxrfvum3  

 

1041. Wu, X., J. Yang, C. Morisseau, B.D. Hammock, H.J. Lehmler. 2016 Aug. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) decreases hepatic and systemic ratios of epoxide to diol metabolites of unsaturated fatty acids in male rats. Toxicol Sci. 152(2):309-22. PMID: 27208083. PMCID: PMC4960907. https://ucdavis.box.com/s/ogalxmzdqjooyx901kltabm54bumjxmm  

 

1051. Harris, T.R., S. Kodani, J. Yang, D.M. Imai and B.D. Hammock. 2016 Dec. An ω-3 enriched diet does not attenuate CCl4-induced hepatic fibrosis. J Nutr Biochem. 38:93-101. PMID: 27732914. PMCID: PMC5102762.https://ucdavis.box.com/s/j4vtlksbv5dot4r4up2nn9heh62w9d6m  

 

1126. Harris TR, Kodani S, Rand AA, Yang J, Imai DM, Hwang SH, Hammock BD. Celecoxib does not protect against fibrosis and inflammation in a carbon tetrachloride-induced model of liver injury. Mol Pharmacol. 2018. Epub 2018/05/31. 94(2):834-841. doi: 10.1124/mol.118.111831. PubMed PMID: 29844231. PMCID: PMC6022802. https://ucdavis.box.com/s/myty4vcdvnhoyce98pzasuorseloays3 

 

1150. Deol P, Yang J, Morisseau C, Hammock BD, Sladek FM. 2019. Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver. Frontiers in Pharmacology. 10(580). doi: 10.3389/fphar.2019.00580. PMID: 31191316. PMCID: PMC6548860. https://ucdavis.box.com/s/4yigsa9hm1ib2frozvl2jknhr4zgrn1e  

 

1218. Zhang J, Tan Y, Chang L, Hammock BD, Hashimoto K. 2020. Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major psychiatric disorders: A role of brain - liver axis. J Affect Disord. 270:131-134. 10.1016/j.jad.2020.03.070.  PMCID: PMC7243919. https://ucdavis.box.com/s/yeep6f42chk37wrwu75tasg05m4yrgib  

 

1270. Sun C-C, Zhang C-Y, Duan J-X, Guan X-X, Yang H-H, Jiang H-L, Hammock BD, Hwang SH, Zhou Y, Guan C-X, Liu S-K, Zhang J. 2020. PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 inflammasome activation in mice. Biochemical and Biophysical Research Communications. 523(4):1020-1026. https://doi.org/10.1016/j.bbrc.2019.12.131. PMID: 31973813. PMCID: PMC7990110. https://ucdavis.box.com/s/1oq8jo24t9mgn26sztr68qp9rj9e3904  

 

1272. Mello A, Hsu MF, Koike S, Chu B, Cheng J, Yang J, Morisseau C, Torok NJ, Hammock BD, Haj FG. 2021. Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease. Cell Mol Gastroenterol Hepatol. 11(3):815-830. 10.1016/j.jcmgh.2020.10.002. PMID: 33068774. PMCID: PMC7851189. https://ucdavis.box.com/s/elv5g6pehyi474hcgqsh1clzgim8yn2u  

 

1289. Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, Liu W, Tan L, Yan M, Li B, He J, Hwang SH, Zhang X, Wang C, Ai D, Hammock BD, Zhu Y. 2019. Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice. Am J Physiol Gastrointest Liver Physiol. 316(4):G527-g538. 10.1152/ajpgi.00148.2018. PMID: 30789748; PMCID: PMC6483021. https://ucdavis.box.com/s/i2oiyarrukert700vs91j3pn23ze164n  

 

1305. Tiwari S, Yang J, Morisseau C, Durbin-Johnson B, Hammock BD, Gomes AV. 2021. Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers. Scientific reports. 11(1):7042. 10.1038/s41598-021-86284-1. PMID: 33782432. PMCID: PMC8007717. https://ucdavis.box.com/s/fhjv1yn0rbd662c5w3i5ur3gfga1m5tb