Sung Hee Hwang
Assistant Project Scientist
Ph.D: Organic Chemistry, University of California, Davis, USA
MS: Organic Chemistry, Sogang University, Seoul, Korea
B.S: Chemistry, Sogang University, Seoul, Korea
Synthesis and biological evaluation of dual inhibitors for cyclooxygenase-2 and double epoxide hydrolase using structure based design and modern medicinal chemistry tools
Design and synthesis of inhibitors for human soluble epoxide hydrolase by parallel and combinatorial synthesis for the lead optimization based of SAR study, physical property determination and PK analysis
Development of novel fluorescent assay reagents for rapid and previse measurement of environmental contaminants by labeling them with two fluorophores called ‘molecular tripod’
89 Briggs Hall
87 Briggs Hall
Associate Research Scientist
Ph.D: Organic Chemistry, University of the Mediterranee, Marseille, France
MS: Food Sciences, ESBANA, Dijon, France
B.S: Food Sciences, University of Nantes, Nantes, France
Study the role of esterases and epoxide hydrolases in biology and xenobiotics metabolism. Toward this purpose, study their mechanism of action, develop specific inhibitors and design fluorescent reporter assay; as well as studying the kinetic of hydrolysis of natural substrates. All of these mainly in mammals; but also in other organisms such as chicken or bacteria. Study also the role of phosphatase activity of sEH.
Assistant Research Scientist
Ph.D: Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China
B.S: Chemistry, Wuhan University, China
Role of soluble expoxide hydrolase in lung diseases including asthma and Chronic Obstructive Pulmonary Disease
Metabolomics method development and applications including profiling the oxylipins such as eicosanoids
Qualification and quantification of small molecules using chromatography and mass spectrometry
Identification of proteins by chromatography and mass spectrometry
80c Briggs Hall
Assistant Research Scientist
Ph.D: Pharmacology, University of California, Davis, USA
B.S: Environmental Toxicology, University of California, Davis, USA
B.A: International Relations/Economics, University of Wisconsin, Madison and Albert Ludwigs Universitat, Germany
1. Research the role of soluble epoxide hydrolase in neurobiology, the biology of bioactive lipids and lipid signaling in normal and pathological conditions with a focus on behavioral pharmacology and nociception using in vivo preclinical techniques to investigate basic science as well as drug discovery.
2. Investigating the roles of lipid metabolites produced in the arachidonic acid cascade and the potential for crosstalk with other lipid mediated systems such as the endocannabinoid system.
3. Investigate both the role of lipids and their regulatory enzymes in chronic neurodegenerative diseases.
4. Investigate the pharmacodynamics of novel analgesics with various mechanisms of action.
220 Everson Hall
206 Everson Hall
Ph.D: University of Chinese Academy of Sciences.
sEH PROTAC project
Toxicity of aflatoxin.