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Research Staff

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Sung Hee Hwang

Assistant Project Scientist

Ph.D: Organic Chemistry, University of California, Davis, USA

MS: Organic Chemistry, Sogang University, Seoul, Korea

B.S: Chemistry, Sogang University, Seoul, Korea

easy.

Research Project:

  1. Synthesis and biological evaluation of dual inhibitors for cyclooxygenase-2 and double epoxide hydrolase using structure based design and modern medicinal chemistry tools

  2. Design and synthesis of inhibitors for human soluble epoxide hydrolase by parallel and combinatorial synthesis for the lead optimization based of SAR study, physical property determination and PK analysis

  3. Development of novel fluorescent assay reagents for rapid and previse measurement of environmental contaminants by labeling them with two fluorophores called ‘molecular tripod’

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Christophe Morisseau

Associate Research Scientist

Ph.D: Organic Chemistry, University of the Mediterranee, Marseille, France

MS: Food Sciences, ESBANA, Dijon, France

B.S: Food Sciences, University of Nantes, Nantes, France

easy.

Research Project:

Study the role of esterases and epoxide hydrolases in biology and xenobiotics metabolism. Toward this purpose, study their mechanism of action, develop specific inhibitors and design fluorescent reporter assay; as well as studying the kinetic of hydrolysis of natural substrates. All of these mainly in mammals; but also in other organisms such as chicken or bacteria. Study also the role of phosphatase activity of sEH.

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Jun Yang

Assistant Research Scientist

Ph.D: Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China

B.S: Chemistry, Wuhan University, China

easy.

Research Project:

  1. Role of soluble expoxide hydrolase in lung diseases including asthma and Chronic Obstructive Pulmonary Disease

  2. Metabolomics method development and applications including profiling the oxylipins such as eicosanoids

  3. Qualification and quantification of small molecules using chromatography and mass spectrometry

  4. Identification of proteins by chromatography and mass spectrometry

89 Briggs Hall

530-754-8884

80c Briggs Hall

530-752-6571

206 Everson Hall

530-752-5109

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Karen Wagner

         Assistant Research Scientist

 

Ph.D: Pharmacology, University of California, Davis, USA

B.S: Environmental Toxicology, University of California, Davis, USA

B.A: International Relations/Economics, University of Wisconsin, Madison and Albert Ludwigs Universitat, Germany

 

Research Project:

1. Research the role of soluble epoxide hydrolase in neurobiology, the biology of bioactive lipids and lipid signaling in normal and pathological conditions with a focus on behavioral pharmacology and nociception using in vivo preclinical techniques to investigate basic science as well as drug discovery.

2. Investigating the roles of lipid metabolites produced in the arachidonic acid cascade and the potential for crosstalk with other lipid mediated systems such as the endocannabinoid system.

3. Investigate both the role of lipids and their regulatory enzymes in chronic neurodegenerative diseases.

4. Investigate the pharmacodynamics of novel analgesics with various mechanisms of action.

220 Everson Hall

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