326. Grant, D.F., J.F. Greene, F. Pinot, B. Borhan, M.F. Moghaddam, B.D. Hammock, B. McCutchen, H. Ohkawa, G. Luo and T.M. Guenthner. 1996. Development of anin situ toxicity assay system using recombinant baculoviruses. Biochem. Pharmacol. 51(4):503-515. [Download]
328. Parker, A.G., F. Pinot, D.F. Grant, J. Spearow and B.D. Hammock. 1996. Regulation of mouse liver microsomal esterases by clofibrate and sexual hormones. Biochem. Pharmacol. 51(5):677-685. [Download]
338. Zeldin, D.C., C.R. Moomaw, N. Jesse, K.B. Tomer, J. Beetham, B. Hammock and S. Wu. 1996. Biochemical characterization of the human liver cytochrome P450 Arachidonic acid epoxygenase pathway Arch. Biochem. Biophys. 330(1):87-96. [Download]
341. Zheng, J. and B.D. Hammock. 1996. Development of polyclonal antibodies for detection of protein modification by 1,2-naphthoquinone. Chem. Res. Toxicol. 9(5):904-909. [Download]
343. Zheng, J., A.E. Mitchell, A.D. Jones and B.D. Hammock. 1996. Haloenol lactone is a new isozyme-selective and active site-directed inactivator of glutathione S-transferase. J. Biol. Chem. 271(34):20421-20425. [Download]
344. Moghaddam, M.F., K. Motoba, B. Borhan, F. Pinot and B.D. Hammock. 1996. Novel metabolic pathways for linoleic acid and arachidonic acid metabolism. Biochim. Biophys. Acta. 1290(3):327-339. [Download]
360. Pinot, F., H. Bosch, J.-P. Salaun, F. Durst, C. Mioskowski and B.D. Hammock. 1997. Epoxide hydrolase activities in the microsomes and the soluble fraction fromVicia sativa seedlings. 35:103-110. [Download]
363. Moghaddam, M.F., D.F. Grant, J. Cheek, J.F. Greene K.C. Williamson and B.D. Hammock. 1997. Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase. Nature Medicine 3(5):562-566. [Download]
368. Hammock, B.D., D.H. Storms, and D.F. Grant. 1997. Epoxide Hydrolases In: Comprehensive Toxicology, (Guengerich, F.P., ed.) Pergamon, Oxford. Vol. 3 Biotransformation, Chapter 18, pp.283-305, Pergamon, Oxford. [Download]
369. Zheng, J., C. Myung, A.D. Jones, and B.D. Hammock. 1997. Evidence of quinone metabolites of naphthalene covalently bound to sulfur nucleophiles of proteins of murine clara cells after exposure to naphthalene. Chem. Res. Toxicol. 10(9):1008-1014. [Download]
370. Müller, F., M. Arand, H. Frank, A. Seidel, W. Hinz, L. Winkler, K. Hänel, E. Blée, J.K. Beetham, B.D. Hammock and F. Oesch. 1997. Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates. Eur. J. Biochem. 245:490-496. [Download]
371. Hammock, B.D. 1997. Are leukotoxins toxic? Nature Medicine. 3(6):502. [Download]
377. Hammock BD, Casida KF. For the fun of science: A discussion with John E. Casida. Archives of insect biochemistry and physiology. 1998;37(1):1-7. doi: doi:10.1002/(SICI)1520-6327(1998)37:1<1::AID-ARCH1>3.0.CO;2-Z. [Download]
378. Zheng, J., G.T. Wurz, T.B. Cadman, M.W. DeGregorio, A.D. Jones, and B.D. Hammock. 1997. Haloenol lactone: A new synergist of cancer chemotherapy in vitro. Biochem. Biophys. Res. Commun. 241:13-17. [Download]
390. Mitchell, A.E., J. Zheng, B.D. Hammock, M. Lo Bello, and A.D. Jones. 1998. Structural and functional consequences of haloenol lactone inactivation of murine and human glutathione S-transferase. Biochemistry. 37(19):6752-6759 [Download]
391. Pinot, F., E.D. Caldas, C. Schmidt, D.G. Gilchrist, A.D. Jones, C.K. Winter and B.D. Hammock. 1997. Characterization of epoxide hydrolase activity in Alternaria alternata f. sp. lycopersici. Possible involvement in toxin production. Mycopathologia 140(1):51-58. [Download]
392. Debernard, S., C. Morisseau, T.F. Severson, L. Feng, H. Wojtasek, G.D. Prestwich and B.D. Hammock. 1998. Expression and characterization of the recombinant juvenile hormone epoxide hydrolase (JHEH) from Manduca sexta. Insect Biochem. Mol. Biol. 28(5-6):409-419. [Download]
394. Morisseau, C., G. Du, J.W. Newman and B.D. Hammock. 1998. Mechanism of mammalian soluble epoxide hydrolase inhibition by chalcone oxide derivatives. Arch. Biochem. Biophy. 356(2):214-228. [Download]
407. Mullen, R.T., R.N. Trelease, H. Duerk, M. Arand, B.D. Hammock, F. Oesch, and D.F. Grant. (1999) Differential subcellular localization of endogenous and transfected soluble epoxide hydrolase in mammalian cells: Evidence for isozyme variants. FEBS Lett. 445(2-3):301-305. [Download]
410. Morisseau, C., B.L. Ward, D.G. Gilchrist and B.D. Hammock. 1999. Multiple epoxide hydrolases in Alternaria alternata f. sp. lycopersici and their relationship to medium composition and host-specific toxin production. Appl. Environ. Microbiol. 65(6):2388-2395. [Download]
411. Draper, A.J. and B.D. Hammock. 1999. Soluble epoxide hydrolase in rat inflammatory cells is indistinguishable from soluble epoxide hydrolase in rat liver. Toxicol. Sci. 50(1):30-35. [Download]
412. Morisseau, C., M.H. Goodrow, D. Dowdy, J. Zheng, J.F. Greene, J.R. Sanborn, and B.D. Hammock. 1999. Potent urea and carbamate inhibitors of soluble epoxide hydrolases. Proc. Natl. Acad. Sci. USA 96(16):8849-8854. [Download]
415. Argiriadi, M.A., C. Morisseau, B.D. Hammock and D.W. Christianson. 1999. Detoxification of environmental mutagens and carcinogens: Structure, mechanism, and evolution of liver epoxide hydrolase. Proc. Natl. Acad. Sci. USA 96(19):10637-10642. [Download]
416. Draper, A.J. and B.D. Hammock. 1999. Inhibition of soluble and microsomal epoxide hydrolase by zinc and other metals. Toxicol. Sci. 52(1):26-32. [Download]
418. Morisseau, C., M. Derbel, T.R. Lane, D. Stoutamire and B.D. Hammock. 1999. Differential induction of hepatic drug-metabolizing enzymes by fenvaleric acid in male rats. Toxicol. Sci. 52(2):148-153. [Download]
419. Lakritz, J., B.S. Winder, J. Noorouz-Zadeh, T.L. Huang, A.R. Buckpitt, B.D. Hammock, and C.G. Plopper. 2000. Hepatic and pulmonary enzyme activities in horses. Am. J. Vet. Res. 61(2):152-157. [Download]
420. Greene, J.F. and B.D. Hammock. 1999. Toxicity of linoleic acid metabolites, in:Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4. (Honn, K.V., L.J. Marnett and S.K. Nigam, Eds.), pp. 471-477. Advances in Experimental Medicine and Biology, Vol. 469, Kluwer Academic/Plenum Publishers, New York, NY. [Download]
422. Greene, J.F., J. Zheng, D.F. Grant and B.D. Hammock. 2000. Cytotoxicity of 1,2-epoxynaphthalene is correlated with protein binding and in situ glutathione depletion in cytochrome P4501A1 expressing Sf-21 cells. Toxicol. Sci. 53(2):352-360. [Download]
426. Draper, A.J. and B.D. Hammock. 2000. Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. Arch. Biochem. Biophys. 376(1):199-205. [Download]
427. Greene, J.F., J.W. Newman, K.C. Williamson and B.D. Hammock. 2000. Toxicity of epoxy fatty acids and related compounds to cells expressing human soluble epoxide hydrolase. Chem. Res. Toxicol. 13(4):217-226. [Download]
429. Greene, J.F., K.C. Williamson, J.W. Newman, C. Morisseau and B.D. Hammock. 2000. Metabolism of monoepoxides of methyl linoleate: Bioactivation and detoxification. Arch. Biochem. Biophys. 376(2):420-432. [Download]
430. Argiriadi, M.A., C. Morisseau, M.H. Goodrow, D.L. Dowdy, B.D. Hammock and D.W. Christianson. 2000. Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation. J. Biol. Chem. 275(20):15265-15270. [Download]
431. Morisseau, C., J.K. Beetham, F. Pinot, S. Debernard, J.W. Newman and B.D. Hammock. 2000. Cress and potato soluble epoxide hydrolases: Purification, biochemical characterization, and comparison to mammalian enzymes. Arch. Biochem. Biophys. 378(2):321-332. [Download]
433. Yamada, T., C. Morisseau, J.E. Maxwell, M.A. Argiriadi, D.W. Christianson and B.D. Hammock. 2000. Biochemical evidence for the involvement of tyrosine in epoxide activation during the catalytic cycle of epoxide hydrolase. J. Biol. Chem. 275(30):23082-23088. [Download]
440. Fanucchi, M.V., A.R. Buckpitt, M.E. Murphy, D.H. Storms, B.D. Hammock and C.G. Plopper. 2000. Development of phase II xenobiotic metabolizing enzymes in differentiating murine Clara cells. Toxicol. Appl. Pharmacol. 168(3):253-267. [Download]
441. Nakagawa, Y., C.E. Wheelock, C. Morisseau, M.H. Goodrow, B.G. Hammock and B.D. Hammock. 2000. 3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues. Bioorganic Med. Chem. 8(11):2663-2673.[Download]
442. Yu, Z., F. Xu, L.M. Huse, C. Morisseau, A.J. Draper, J.W. Newman, C. Parker, L. Graham, M.M. Engler, B.D. Hammock, D.C. Zeldin and D.L. Kroetz. 2000. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ. Res. 87(11):992-998. [Download]