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StumbleUponThe Laboratory of Dr. Bruce D. Hammock
The biochemical basis of human and environment interactions has been the long term theme of research and training in the Hammock Laboratory. Led by Dr. Hammock, a member of the National Academy of Science, our team of over 40 scientists and students employ a multidisciplinary, integrated approach to research that delves into basic questions of biology and biochemistry that have practical implications for improving both human and environmental health.
[To know more about our research]
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Guodong and UC reseachers' key discovery involving omega-3 fatty acids and cancer
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UC Davis researchers have discovered a key mechanism by which dietary omega-3 fatty acids (fish oils) could reduce the tumor growth and spread of cancer, a disease that kills some 580,000 Americans a year. In groundbreaking research, the team of 16 scientists led by Dr. Guodong Zhang of the Bruce Hammock laboratory discovered cytochrome P450 epoxygenase metabolites of omega-3 fatty acid DHA or epoxy docosapentaenoic acids (EDPs) block blood supply to the tumor and thus inhibit tumor growth and metastasis.
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A therapy for cardiometabolic syndrome Scientists at the Medical College of Wisconsin and UC Davis, led by Dr. John Imig and Dr. Hammock have determined the synergistic actions of inhibiting soluble epoxide hydrolase with tAUCB and activating peroxisome proliferator-activator receptorγ with the thiazolidinedione rosiglitazone on the pathological progression of cardiometabolic syndrome. Full Story |
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To test experimental drug for laminitis in horses A Soluble Epoxide Hydrolase Inhibitor developed in Dr. Hammock's lab has shown positive results in treating late stage laminitis, a non-treatable, painful and often life-threatening foot-related disease in horses. Clinical trials are currently underway in horses to determine safety and efficacy. Full Story |
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