Epoxide
Hydrolase Bibliography
Bruce D. Hammock
Published:
001. Kamimura, H., B.D.
Hammock, I. Yamamoto and
J.E. Casida. 1972. A potent juvenile hormone
mimic,
1-(4'-ethylphenoxy)-6,7-epoxy-3,7-dimethyl-2-octene, labeled with
tritium in
either the ethylphenyl- or geranyl-derived moiety.
J. Agric. Food Chem.
20(2):439-442.
002. Gill, S.S., B.D. Hammock,
I. Yamamoto and
J.E. Casida. 1972. Preliminary
chromatographic studies on the
metabolites and photodecomposition products of the juvenoid
1-(4'-ethylphenoxy-6,7-epoxy-3,7- dimethyl-2-octene.
In: Insect Juvenile Hormones: Chemistry and
Action, (Menn, J.J. and M. Beroza, eds.), Academic Press, New York, pp.
177-189.
003. Gill, S.S., B.D. Hammock
and J.E.
Casida. 1974. Mammalian metabolism and
environmental
degradation of the juvenoid 1-(4'- ethylphenoxy)-3,7-dimethyl-6,7-epoxy-trans-2-octene and related
compounds. J.
Agric. Food Chem. 22(3):386-395.
004. Hammock, B.D., S.S. Gill
and J.E.
Casida. 1974. Synthesis and
morphogenetic activity of
derivatives and analogs of aryl geranyl ether juvenoids. J. Agric. Food Chem. 22(3):379-385.
006. Hammock, L.G., B.D.
Hammock and J.E.
Casida. 1974. Detection and analysis of
epoxides with 4-(p-nitrobenzyl)-pyridine. Bull. Environ. Contam.
Toxicol. 12(6):759-764.
007. Hammock, B.D., S.S. Gill,
L.G. Hammock and
J.E. Casida. 1975. Metabolic O-dealkylation
of 1-(4'-ethylphenoxy)-3,7-dimethyl-7-methoxy or ethoxy-trans-2-octene,
potent juvenoids.
Pestic. Biochem. Physiol.
5:12-18.
010.
Hammock, B.D., S.S. Gill, V. Stamoudis and
L.I. Gilbert. 1976. Soluble mammalian epoxide
hydratase: action
on juvenile hormone and other terpenoid epoxides.
Comp. Biochem. Physiol.
53B:263-265.
011.
Hammock, B.D. and G.B. Quistad.
1976.
The degradative metabolism of juvenoids by insects. In: The Juvenile Hormones,
(Gilbert, L.E.,
eds.), Plenum Press, New York, pp. 374-393.
015.
Hammock, B.D., E. Kuwano, A. Ketterman, R.H.
Scheffrahn, S.N. Thompson and D. Sallume.
1978. Acute
toxicity and
developmental effects of analogues of ethyl a-(4-
chlorophenoxy)-a-methylpropionate on two insects, Oncopeltus
fasciatus and Tenebrio
molitor. J.
Agric. Food Chem. 26(1):166-170.
021.
Mumby, S.M. and B.D. Hammock.
1979.
A partition assay for epoxide hydrases acting on insect
juvenile hormone
and an epoxide-containing juvenoid.
Anal. Biochem. 92:16-21.
024.
Mumby, S.M. and B.D. Hammock.
1979.
Substrate selectivity and stereochemistry of enzymatic
epoxide hydration
in the soluble fraction of mouse liver.
Pestic. Biochem. Physiol.
11:275-284.
026.
Gill, S.S. and B.D. Hammock.
1979.
Hydration of cis- and trans-epoxymethyl stearates by the
cytosolic epoxide hydrase of mouse liver.
Biochem. Biophys. Res. Commun.
89(3):965-971.
028.
Mumby, S.M. and B.D. Hammock.
1979.
Stability of epoxide-containing juvenoids to dilute
aqueous acid. Agric.
Food Chem. 27(8):1223-1228.
031.
Hammock, B.D., S.S. Gill, S.M. Mumby and K.
Ota. 1980. Comparison of epoxide
hydrases in the soluble
and microsomal fractions of mammalian liver.
In: Molecular Basis of Environmental Toxicity, (Bhatnagar,
R.S., eds.),
Ann Arbor Science Publishers, Ann Arbor, Michigan, pp. 229-272.
032.
Gill, S.S. and B.D. Hammock.
1980.
Distribution and properties of a mammalian soluble epoxide
hydrase. Biochem.
Pharmacol. 29:389-395.
033.
Ota, K. and B.D. Hammock.
1980.
Cytosolic and microsomal epoxide hydrolases: differential
properties in
mammalian liver. Science. 207:1479-1481.
034.
Hammock, B.D., M. El-Tantawy, S.S. Gill, L.
Hasegawa, C.A. Mullin and K. Ota.
1980. Extramicrosomal
epoxide
hydration. In:
Microsomes, Drug
Oxidations, and Chemical Carcinogenesis, (Coon, M.J., A.H. Conney, R.
Estabrook, H.H. Gelboin, J.R. Gillette and B.J. O'Brien, eds.),
Academic Press,
New York, pp. 655-658.
035.
El-Tantawy, M.A. and B.D. Hammock.
1980.
The effect of hepatic microsomal and cytosolic subcellular
fractions on
the mutagenic activity of epoxide-containing compounds in the Salmonella assay.
Mutat. Res.
79:59-71.
036.
Mullin, C.A. and B.D. Hammock.
1980.
A rapid radiometric assay for mammalian cytosolic epoxide
hydrolase. Anal.
Biochem. 106:476-485.
037.
Ivie, G.W., J.T. MacGregor and B.D.
Hammock. 1980. Mutagenicity of psoralen
epoxides. Mutat.
Res.
79:73-77.
039.
Hammock, B.D., M. Ratcliff and D.A.
Schooley. 1980. Hydration of an 180
epoxide by a
cytosolic epoxide hydrolase from mouse liver.
Life Sci. 27:1635-1641.
042.
Hammock, B.D.
1981. Metabolism
and
environmental fate of juvenoids. In:
Regulation of Insect Development and Behavior, (Sehnal, F., A. Zabza,
J.J. Menn
and B. Cymborowski, eds.), Wroclaw Technical University Press, Wroclaw,
Poland,
pp. 841-852.
043.
Gill, S.S. and B.D. Hammock.
1981.
Epoxide hydrolase activity in the mitochondrial fraction
of mouse
liver. Nature. 291(5811):167-168.
046.
Hammock, B.D. and G.B. Quistad.
1981. Metabolism
and mode of action of juvenile hormone, juvenoids, and other insect
growth
regulators. In:
Progress in Pesticide
Biochemistry, (Hutson, D.H. and T.R. Roberts, eds.), John Wiley
& Sons,
Ltd., Sussex, England, pp. 1-83, Volume 1.
047.
Guenthner, T.M., B.D. Hammock, U. Vogel and
F. Oesch. 1981. Cytosolic and microsomal
epoxide hydrolases
are immunologically distinguishable from each other in the rat and
mouse. J. Biol.
Chem. 256(7):3163-3166.
048.
Gill, S.S. and B.D. Hammock.
1981.
Epoxide hydrolase activity in the mitochondrial and
submitochondrial
fractions of mouse liver. Biochem.
Pharmacol. 30(15):2111-2120.
054.
Mullin, C.A. and B.D. Hammock.
1982.
Chalcone oxides - potent selective inhibitors of cytosolic
epoxide
hydrolase. Arch.
Biochem. Biophys. 216(2):423-439.
055.
Hasegawa, L.S. and B.D. Hammock.
1982.
Spectrophotometric assay for mammalian cytosolic epoxide
hydrolase using
trans-stilbene oxide as the
substrate. Biochem.
Pharmacol. 31(11):1979-1984.
062.
Gill, S.S., S.I. Wie, T.M. Guenthner, F.
Oesch and B.D. Hammock. 1982. Rapid and sensitive
enzyme-linked immunosorbent
assay for the microsomal epoxide hydrolase.
Carcinogenesis. 3(11):1307-1310.
063.
Hammock, B.D. and L.S. Hasagawa.
1983.
Differential substrate selectivity of murine hepatic
cytosolic and
microsomal epoxide hydrolases. Biochem.
Pharmacol. 32(7):1155-1164.
064.
Chacos, N., J. Capdevila, J.R. Falck, S.
Manna, C. Martin-Wixtrom, S.S. Gill, B.D. Hammock and R.W. Estabrook. 1983.
The reaction of arachidonic acid epoxides
(epoxyeicosatrienoic acids)
with a cytosolic epoxide hydrolase.
Arch. Biochem. Biophys.
223(2):639-648.
066.
Gill, S.S., K. Ota and B.D. Hammock.
1983.
Radiometric assays for mammalian epoxide hydrolases and
glutathione S-transferase. Anal. Biochem. 131:273-282.
068.
Gill, S.S., K. Ota, B. Ruebner and B.D.
Hammock. 1983. Microsomal and cytosolic
epoxide hydrolases
in rhesus monkey liver, and in normal and neoplastic human liver. Life Sci.
32:2693-2700.
069.
Hammock, B.D. and K. Ota.
1983.
Differential induction of cytosolic epoxide hydrolase,
microsomal
epoxide hydrolase, and glutathione S-transferase
activities. Toxicol. App. Pharmacol. 71:254-265.
075.
Hammock, B.D., D.N. Loury, D.E. Moody, B.
Ruebner, R. Baselt, K.M. Milam, P. Volberding, A. Ketterman and R.
Talcott. 1984. A methodology for the
analysis of the
preneoplastic antigen.
Carcinogenesis. 5(11):1467-1473.
080.
Prestwich, G.D., I. Lucarelli, S.-K. Park,
D.N. Loury, D.E. Moody and B.D. Hammock.
1985. Cyclopropyl
oxiranes:
Reversible inhibitors of cytosolic and microsomal epoxide hydrolases. Arch. Biochem. Biophys. 237(2):361-372.
082.
Prestwich, G.D. and B.D. Hammock.
1985.
Rapid purification of cytosolic epoxide hydrolase from
normal and
clofibrate-treated animals by affinity chromatography.
Proc. Natl. Acad. Sci. USA
82:1663-1667.
087.
Hammock, B.D., D.E. Moody and A.
Sevanian. 1985. Epoxide hydrolases in the
catabolism of
sterols and isoprenoids. In:
Methods in
Enzymology, Volume III, Steroids and Isoprenoids, Part B, (Law, J.H.
and H.C.
Rilling, eds.), Academic Press, Orlando, Florida, pp. 303-311.
089.
Loury, D.N., D.E. Moody, B.W. Kim and B.D.
Hammock. 1985. Effect of dietary
clofibrate on epoxide
hydrolase activity in tissues of mice.
Biochem. Pharmacol. 34(10):1827-1833.
090.
Moody, D.E., D.N. Loury and B.D.
Hammock. 1985. Epoxide metabolism in the
liver of mice
treated with clofibrate (ethyl-a-(p-chlorophenoxyisobutyrate)),
a peroxisome proliferator. Toxicol.
Appl. Pharmacol. 78:351-362.
091.
Wixtrom, R.N. and B.D. Hammock.
1985.
Membrane-bound and soluble-fraction epoxide hydrolases:
Methodological
aspects. In:
Biochemical Pharmacology
and Toxicology, Vol. 1: Methodological Aspects of Drug Metabolizing
Enzymes,
(Zakim, D. and D.A. Vessey, eds.), John Wiley & Sons, Inc., New
York, pp.
1-93.
094.
Prestwich, G.D., J.-W. Kuo, S.K. Park, D.N.
Loury and B.D. Hammock. 1985. Inhibition of epoxide
metabolism by a,b-epoxyketones
and isosteric analogs. Arch.
Biochem.
Biophys. 242(1):11-15.
098.
Hammock, B.D., G.D. Prestwich, D.N. Loury,
P.Y.K. Cheung, W.S. Eng, S.K. Park, D.E. Moody, M.H. Silva and R.N.
Wixtrom. 1986. Comparison of crude and
affinity purified
cytosolic epoxide hydrolases from hepatic tissue of control and
clofibrate-fed
mice. Arch.
Biochem. Biophys. 244(1):292-309.
100.
Ottea, J.A. and B.D. Hammock.
1986.
Optimization of assay conditions for epoxide metabolizing
enzymes in Trichoplusia ni. Insect Biochem. 16(2):319-325.
102.
Moody, D.E., M.H. Silva and B.D.
Hammock. 1986. Epoxide hydrolysis in the
cytosol of rat
liver, kidney, and testis. Measurement
in the presence of glutathione and the effect of dietary clofibrate. Biochem. Pharmacol. 35(13):2073-2080.
107.
Helferich, W.G., E.G. Carroad, M.D. Easter,
D.E. Moody, B.D. Hammock and L.R. Shull.
1986. Effect
of
medroxyprogesterone acetate on hepatic and placental drug metabolism in
rats. Biochem.
Pharmacol. 35(20):3655-3658.
109.
Wisniewski, J.A., D.E. Moody, B.D. Hammock
and L.R. Shull. 1987. Interlobular distribution
of hepatic
xenobiotic-metabolizing enzyme activities in cattle, goats and sheep.
J. Anim.
Sci. 64:210-215.
110.
Gillette, D.M., R.D. Corey, W.G. Helferich,
J.M. McFarland, L.J. Lowenstine, D.E. Moody, B.D. Hammock and L.R.
Shull. 1987.
Comparative toxicology of tetrachlorobiphenyls in mink and
rat. I.
Changes in hepatic enzyme activity and smooth endoplasmic
reticulum
volume. Fundam.
Appl. Toxicol. 8:5-14.
111.
Moody, D.E., D.N. Loury and B.D.
Hammock. 1987. Immunochemical
determination of microsomal
epoxide hydrolase (preneoplastic antigen) in extrahepatic tissue. Biochem. Pharmacol. 36(4):570-572.
113.
Miyamoto, T., M. Silva and B.D. Hammock.
1987.
Inhibition of epoxide hydrolases and glutathione S-transferases by 2-, 3-, and
4-substituted derivatives of
4'-phenylchalcone and its oxide. Arch.
Biochem. Biophys. 254(1):203-213.
115.
Silva, M.H. and B.D. Hammock.
1987.
Affinity purification of cytosolic epoxide hydrolase from
human, rhesus
monkey, baboon, rabbit, rat and mouse liver.
Comp. Biochem. Physiol.
87B(1):95-102.
116.
Munger, C.E., G.W. Ivie, R.J. Christopher, B.D.
Hammock and T.D. Phillips. 1987. Acetylation/deacetylation
reactions of T-2,
acetyl T-2, HT-2 and acetyl HT-2 toxins in bovine rumen fluid in vitro.
J. Agric. Food Chem.
35(3):354-358.
118.
Ottea, J.A., L.G. Harshman and B.D.
Hammock. 1987. Patterns of epoxide
metabolism by epoxide
hydrolase and glutathione S-transferase
associated with age and genotype in Drosophila
melanogaster. Mutat.
Res. 177:247-254.
119.
Moody, D.E. and B.D. Hammock.
1987.
The effect of tridiphane
(2-(3,5-dichloropohenyl)-2-(2,2,2-trichloroethyl) oxirane) on hepatic
epoxide-metabolizing enzymes: Indications of peroxisome proliferation. Toxicol. Appl. Pharmacol. 89:37-48.
121.
Ashour, M.-B.A., D.E. Moody and B.D.
Hammock. 1987. Apparent induction of
microsomal-carboxylesterase activities in tissues of clofibrate-fed
mice and
rats. Toxicol.
Appl. Pharmacol. 89:361-369.
122.
Narloch, B.A., M.P. Lawton, D.E. Moody, B.D.
Hammock and L.R. Shull. 1987. The effects of dicofol on
induction of
hepatic microsomal metabolism in rats.
Pestic. Biochem. Physiol.
28:362-370.
125.
Moody, D.E. and B.D. Hammock.
1987.
Purification of microsomal hydrolase from liver of rhesus
monkey:
Partial separation of cis- and trans-stilbene oxide hydrolase. Arch. Biochem. Biophys. 258(1):156-166.
127.
Ashour, M.-B.A., S.J. Gee and B.D. Hammock. 1987.
Use of a 96-well microplate reader for measuring routine
enzyme
activities. Anal.
Biochem. 166:353-360.
131.
Ottea, J.A., F.W. Plapp and B.D.
Hammock. 1987. Biochemical and genetic
analysis of
epoxide-metabolizing enzymes in susceptible and resistant house flies, Musca domestica L.
Pestic. Biochem. Physiol.
29:138-145.
134.
Magdalou, J. and B.D. Hammock.
1987.
Metabolism of tridiphane
(2-(3,5-dichlorophenyl)-2(2,2,2-trichloroethyl)
oxirane) by hepatic epoxide hydrolases and glutathione S-transferases
in mouse.
Toxicol. Appl. Pharmacol.
91:439-449.
135.
Wixtrom, R.N., M.H. Silva and B.D.
Hammock. 1988. Affinity purification of
cytosolic epoxide
hydrolase using derivatized epoxy-activated Sepharose gels. Anal. Biochem. 169:71-80.
137.
Moody, D.E., G.A. Clawson, D.A. Geller, L.A.
Taylor, J. Button, D.N. Loury, B.D. Hammock and E.A. Smuckler. 1988.
Sodium cholate extraction of rat liver nuclear
xenobiotic-metabolizing
enzymes. Biochem.
Pharmacol. 37(7):1331-1341.
138.
Silva, M.H., R.N. Wixtrom and B.D.
Hammock. 1988. Epoxide-metabolizing
enzymes in mammary gland
and liver from BALB/c mice and effects of inducers on enzyme activity. Cancer Res.
48:1390-1397.
141.
Ottea, J.A., L.G. Harshman and B.D.
Hammock. 1988. Novel assay for
determining the metabolic
fate of juvenile hormone III: A study with Drosophila
melanogaster. Arch.
Insect Biochem.
Physiol. 8:25-37.
143.
Magdalou, J. and B.D. Hammock.
1988.
1,2-Epoxycycloalkanes: Substrates and inhibitors of
microsomal and
cytosolic epoxide hydrolases in mouse liver.
Biochem. Pharmacol.
37(14):2717-2722.
144.
Finley, B.L. and B.D. Hammock.
1988.
Increased cholesterol epoxide hydrolase activity in
clofibrate-fed
animals. Biochem.
Pharmacol. 37(16):3169-3175.
146.
Wixtrom, R.N. and B.D. Hammock.
1988.
Continuous spectrophotometric assays for cytosolic epoxide
hydrolase. Anal.
Biochem. 174:291-299.
147.
Wixtrom, R.N., M.H. Silva and B.D. Hammock. 1988.
Cytosolic epoxide hydrolase in human placenta. Placenta.
9:559-563.
154.
Moody, D.E., B.D. Hammock, B.H. Ruebner, D.W.
Hillman and J.H. Hillman. 1989. Immunochemical comparison
of human and rhesus
monkey liver microsomal and the hepatocellular carcinoma-induced human
serum
epoxide hydrolases (preneoplastic antigens): Basis for an enzyme-linked
immunoabsorbent assay.
Carcinogenesis.
10(2):343-349.
155.
Lauren, D.J., P.P. Halarnkar, B.D. Hammock
and D.E. Hinton. 1989. Microsomal and cytosolic
epoxide hydrolase,
and glutathione S-transferase
activities in the gill, liver, and kidney of the rainbow trout, Salmo gairdneri: Baseline levels and
optimization of assay conditions.
Biochem. Pharmacol.
38(6):881-887.
156.
DiBiasio, K.W., M.H. Silva, B.D. Hammock and
L.R. Shull. 1989. Effects of hepatic
inducers on testicular
epoxide-metabolizing enzymes in the rat and mouse.
Fundam. Appl. Toxicol.
12:449-459.
161.
Pham, M.A., J. Magdalou, M. Totis, S.
Fournel-Gigleux, G. Siest and B.D. Hammock.
1989. Characterization
of
distinct forms of cytochromes P-450, epoxide metabolizing enzymes and
UDP-glucuronosyltransferases in rat skin.
Biochem. Pharmacol.
38(13):2187-2194.
162.
Halarnkar, P.P., R.N. Wixtrom, M.H. Silva and
B.D. Hammock. 1989. Catabolism of epoxy fatty
esters by the
purified epoxide hydrolase from mouse and human liver.
Arch. Biochem. Biophys.
272(1):226-236.
174.
Dietze, E.C., J. Magdalou and B.D.
Hammock. 1990. Human and murine cytosolic
epoxide hydrolase:
Physical and structural properties.
Int.
J. Biochem. 22(5):461-470.
178.
Harshman, L.G. and B.D. Hammock.
1990.
The use of Drosophila
melanogaster
for in situ biomonitoring. In: In
Situ Evaluations of the Biological Hazards of Environmental
Pollutants.,
(Sandhu, S.S., W.R. Lower, F.J.d. Serres, W.A. Suk and R.R. Tice,
eds.), Plenum
Press, New York, pp. 191-194.
188.
DiBiasio, K.W., M.H. Silva, L.R. Shull, J.W.
Overstreet, B.D. Hammock and M.G. Miller.
1991. Xenobiotic
metabolizing
enzyme activities in rat, mouse, monkey, and human testes. Drug Metab. Dispos. 19(1):227-232.
189.
Messeguer, A., F. Sanchez-Baeza, J. Casas and
B.D. Hammock. 1991. Use of dimethyldioxirane
in the preparation
of epoxy derivatives related to insect juvenile hormones. Tetrahedron.
47(7):1291-1302.
190.
Casas, J., L.G. Harshman, A. Messeguer, E.
Kuwano and B.D. Hammock. 1991. In
vitro metabolism of juvenile hormone III and juvenile hormone
III bisepoxide
by Drosophila melanogaster and
mammalian cytosolic epoxide hydrolase.
Arch. Biochem. Biophys.
286(1):153-158.
191.
Casas, J., L.G. Harshman and B.D.
Hammock. 1991. Epoxide hydrolase activity
on juvenile
hormone in Manduca sexta. Insect Biochem. 21(1):17-26.
192.
Moody, D.E., K.A. Montgomery, M.B.A. Ashour
and B.D. Hammock. 1991. Effects of environmentally
encountered
epoxides on mouse liver epoxide-metabolizing enzymes.
Biochem. Pharmacol. 41(11):1625-1637.
195.
Grant, D.F., E.C. Dietze and B.D.
Hammock. 1991. Glutathione S-transferase
isozymes in Aedes
aegypti: Purification, characterization, and isozyme-specific
regulation. Insect
Biochem. 21(4):421-433.
198.
Dietze, E.C., E. Kuwano, J. Casas and B.D.
Hammock. 1991. Inhibition of cytosolic
epoxide hydrolase by trans-3-phenylglycidols. Biochem. Pharmacol. 42(6):1163-1175.
203.
Harshman, L.G., J. Casas, E.C. Dietze and
B.D. Hammock. 1992. Epoxide hydrolase
activities in Drosophila melanogaster. Insect Biochem. 21(8):887-894.
205.
Moody, D.E., B.A. Narloch, L.R. Shull and
B.D. Hammock. 1991. The effect of structurally
divergent
herbicides on mouse liver xenobiotic-metabolizing enzymes
(P-450-dependent
mono-oxygenases, epoxide hydrolases and glutathione S-transferases)
and caritine acetyltransferase. Toxicology
Letters. 59:175-185.
208.
Nourooz-Zadeh, J., T. Uematsu, B. Borhan,
M.J. Kurth and B.D. Hammock. 1992. Characterization of the
cytosolic epoxide
hydrolase-catalyzed hydration products from 9,10:12,13-diepoxy stearic
esters. Arch.
Biochem. Biophys. 294(2):675-685.
209.
Halarnkar, P.P., J. Nourooz-Zadeh, E. Kuwano,
A.D. Jones and B.D. Hammock. 1992. Formation of cyclic
products from the
diepoxide of long-chain fatty esters by cytosolic epoxide hydrolase. Arch. Biochem. Biophys. 294(2):586-593.
214.
Székács, A., B. Bordás
and B.D. Hammock. 1992.
Transition state analog enzyme inhibitors:
Structure-activity
relationships of trifluoromethyl ketones.
In: Rational Approaches to Structure, Activity, and
Ecotoxicology of
Agrochemicals., (Draber, W. and T. Fujita, eds.), CRC Press, Boca
Raton,
Florida, pp. 219-249.
219.
Moody, D.E., D.N. Loury, B.D. Hammock, B.H.
Ruebner, J.M. Cullen, J.H. Hillman, D.W. Hillman, M.S. Rao, W.T.
London,
H.-W.L. Hann, I. Millman and M.J. Griffin.
1992. Serum
epoxide hydrolase
(preneoplastic antigen) in human and experimental liver injury. Cancer Epidemiol.
Biomarkers &
Prevention. 1:395-403.
220.
Grant, D.F. and B.D. Hammock.
1992.
Genetic and molecular evidence for a trans-acting
regulatory locus controlling glutathione S-transferase-2
expression in Aedes aegypti. Mol. Gen. Genet. 234:169-176.
221.
Nourooz-Zadeh, J., B.S. Winder, E.C. Dietze,
C.S. Giometti, S.L. Tollaksen and B.D. Hammock.
1992. Biochemical
characterization of a variant form of cytosolic epoxide hydrolase
induced by
parental exposure to N-ethyl-N-nitrosourea.
Comp. Biochem. Physiol.
103C(1):207-214.
225.
Dietze, E.C., E. Kuwano and B.D.
Hammock. 1993. The interaction of
cytosolic epoxide
hydrolase with chiral epoxides. Int.
J.
Biochem. 25(1):43-52.
227.
Dietze, E.C., J. Stephens, J. Magdalou, D.M.
Bender, M. Moyer, B. Fowler and B.D. Hammock.
1993. Inhibition
of human and
murine cytosolic epoxide hydrolase by group-selective reagents. Comp. Biochem. Physiol. 104B(2):299-308.
228.
Dietze, E.C., J. Casas, E. Kuwano and B.D.
Hammock. 1993. Inhibition of epoxide
hydrolase from human,
monkey, bovine, rabbit, and murine liver by trans-3-phenylglycidols. Comp. Biochem. Physiol. 104B(2):309-314.
231.
Parker, L.M., D.J. Lauren, B.D. Hammock, B.
Winder and D.E. Hinton. 1993. Biochemical and
histochemical properties of
hepatic tumors of rainbow trout, Oncorhynchus
mykiss. Carcinogenesis. 14(2):211-217.
235.
Borhan, B., J. Nourooz-Zadeh, T. Uematsu,
B.D. Hammock and M.J. Kurth. 1993. Stereochemical aspects of
cytosolic epoxide
hydrolase hydration of methyl diepoxystearates.
Tetrahedron.
49(13):2601-2612.
237.
Zeldin, D.C., J. Kobayashi, J.R. Falck, B.S.
Winder, B.D. Hammock, J.R. Snapper and J.H. Capdevila.
1993.
Regio- and enantiofacial selectivity of
epoxyeicosatrienoic acid
hydration by cytosolic epoxide hydrolase.
J. Biol. Chem. 268(9):6402-6407.
240.
Beetham, J.K., T. Tian and B.D. Hammock.
1993.
cDNA cloning and expression of a soluble epoxide hydrolase
from human
liver Arch.
Biochem. Biophys. 305(1):197-201.
241.
Grant, D.F., D.H. Storms and B.D.
Hammock. 1993. Molecular cloning and
expression of murine
liver soluble epoxide hydrolase. J.
Biol. Chem. 268(23):17628-17633.
242.
Winder, B.S., J. Nourooz-Zadeh, R.R.
Isseroff, M.F. Moghaddam and B.D. Hammock.
1993. Properties
of enzymes
hydrating epoxides in human epidermis and liver. Int. J. Biochem.
25(9):1291-1301.
253.
Cho, M., R. Jedrychowski, B. Hammock and A.
Buckpitt. 1994. Reactive naphthalene
metabolite binding to
hemoglobin and albumin. Fundam.
Appl.
Toxicol. 22:26-33.
254.
Dietze, E.C., E. Kuwano and B.D.
Hammock. 1994. Spectrophotometric
substrates for cytosolic
epoxide hydrolase. Anal.
Biochem. 216:176-187.
256.
Hammock, B.D., F. Pinot, J.K. Beetham, D.F.
Grant, M.E. Arand and F. Oesch.
1994. Isolation
of a putative
hydroxyacyl enzyme intermediate of an epoxide hydrolase. Biochem. Biophys. Res.
Commun. 198(3):850-856.
259.
Arand, M., D.F. Grant, J.K. Beetham, T.
Friedberg, F. Oesch and B.D. Hammock.
1994. Sequence
similarity of
mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase
and other
related proteins. FEBS
Letters. 338(3):251-256.
264.
Grant, D.F., J.L. Spearow, D.H. Storms, S.
Edelhoff, D.A. Adler, C.M. Disteche, B.A. Taylor and B.D. Hammock. 1994.
Chromosomal mapping and expression levels of a mouse
soluble epoxide
hydrolase gene. Pharmacogenetics. 4(2):64-72.
265.
Grant, D.F., D.E. Moody, J. Beetham, D.H.
Storms, M.F. Moghaddam, B. Borhan, F. Pinot, B. Winder and B.D. Hammock. 1994.
The response of soluble epoxide hydrolase and other
hydrolytic enzymes
to peroxisome proliferators. In:
Peroxisome Proliferators: Unique
Inducers of Drug-Metabolizing Enzymes, (Moody, D.E., eds.), CRC Press,
Inc.,
Boca Raton, Florida, pp. 97-112.
266.
Stapleton, A., J.K. Beetham, F. Pinot, J.E.
Garbarino, D.R. Rockhold, M. Friedman, B.D. Hammock and W.R. Belknap. 1994.
Cloning and expression of soluble epoxide hydrolase from
potato. Plant J.
6(2):251-258.
267.
Kiyosue, T., J.K. Beetham, F. Pinot, B.D.
Hammock, K. Yamaguchi-Shinozaki and K. Shinozaki.
1994.
Characterization of an Aradibopsis
cDNA for a soluble epoxide hydrolase gene that is inducible by auxin
and water
stress. Plant J. 6(2):259-269.
273.
Gill, S.J., D.F. Grant, J.K. Beetham, C.
Chang and B.D. Hammock. 1994. Peroxisomal proliferation
and subcellular
localization of soluble epoxide hydrolase: Role of peroxisomal
targeting
sequences. In:
Peroxisome Proliferators:
Unique Inducers of Drug-Metabolizing Enzymes, (Moody, D.E., eds.), CRC
Press,
Inc., Baca Raton, Florida, pp. 113-121.
276.
Beetham, J.K., D. Grant, M. Arand, J.
Garbarino, T. Kiyosue, F. Pinot, F. Oesch, W.R. Belknap, K. Shinozaki
and B.D.
Hammock. 1995. Gene evolution of epoxide
hydrolases and
recommended nomenclature. DNA
Cell
Biol. 14(1):61-71.
277.
Borhan, B., S. Nazarian, E.M. Stocking, B.D.
Hammock and M.J. Kurth. 1994. An efficient preparation
of 18O-labeled
epoxides. J. Org.
Chem. 59:4316-4318.
281.
Zeldin, D.C., S. Wei, J.R. Falck, B.D.
Hammock, J.R. Snapper and J.H. Capdevila.
1995. Metabolism
of epoxyeicosatrienoic
acids by cytosolic epoxide hydrolase: Substrate structural determinants
of
asymmetric catalysis. Arch.
Biochem.
Biophys. 316(1):443-451.
289.
Pinot, F., D.F. Grant, J.K. Beetham, A.G.
Parker, B. Borhan, S. Landt, A.D. Jones and B.D. Hammock. 1995.
Molecular and biochemical evidence for the involvement of
the
Asp333-His523 pair in the catalytic mechanism of soluble epoxide
hydrolase. J. Biol.
Chem. 270(14):7968-7974.
298.
Pinot, F., D.F. Grant, J.L. Spearow, A.G.
Parker and B.D. Hammock. 1995. Differential regulation of
soluble epoxide
hydrolase by clofibrate and sexual hormones in liver and kidneys of
mice. Biochem.
Pharmacol. 50(4):501-508.
318.
Borhan, B., T. Mebrahtu, S. Nazarian, M.J.
Kurth and B.D. Hammock. 1995. Improved radiolabeled
substrates for soluble
epoxide hydrolase. Anal.
Biochem. 231(1):188-200.
321.
Borhan, B., A.D. Jones, F. Pinot, D.F. Grant,
M.J. Kurth and B.D. Hammock. 1995. Mechanism of soluble
epoxide hydrolase:
Formation of an a-hydroxy
ester-enzyme intermediate through Asp-333.
J. Biol. Chem.
270(45):26923-26930.
326.
Grant, D.F., J.F. Greene, F. Pinot, B.
Borhan, M.F. Moghaddam, B.D. Hammock, B. McCutchen, H. Ohkawa, G. Luo
and T.M.
Guenthner. 1996. Development of an in situ toxicity assay system using
recombinant baculoviruses. Biochem.
Pharmacol. 51(4):503-515.
328.
Parker, A.G., F. Pinot, D.F. Grant, J.
Spearow and B.D. Hammock. 1996. Regulation of mouse liver
microsomal
esterases by clofibrate and sexual hormones.
Biochem. Pharmacol.
51(5):677-685.
338.
Zeldin, D.C., C.R. Moomaw, N. Jesse, K.B.
Tomer, J. Beetham, B. Hammock and S. Wu.
1996. Biochemical
characterization of the human liver cytochrome P450 Arachidonic acid
epoxygenase pathway Arch.
Biochem.
Biophys. 330(1):87-96.
341.
Zheng, J. and B.D. Hammock.
1996.
Development of polyclonal antibodies for detection of
protein
modification by 1,2-naphthoquinone.
Chem. Res. Toxicol. 9(5):904-909.
343.
Zheng, J., A.E. Mitchell, A.D. Jones and B.D.
Hammock. 1996. Haloenol lactone is a new
isozyme-selective
and active site-directed inactivator of glutathione S-transferase. J. Biol.
Chem. 271(34):20421-20425.
344.
Moghaddam, M.F., K. Motoba, B. Borhan, F. Pinot
and B.D. Hammock. 1996. Novel metabolic pathways
for linoleic acid
and arachidonic acid metabolism.
Biochim. Biophys. Acta.
1290(3):327-339.
360.
Pinot, F., H. Bosch, J.-P. Salaun, F. Durst,
C. Mioskowski and B.D. Hammock.
1997. Epoxide
hydrolase
activities in the microsomes and the soluble fraction from Vicia sativa seedlings.
35:103-110.
363.
Moghaddam, M.F., D.F. Grant, J. Cheek, J.F.
Greene K.C. Williamson and B.D. Hammock.
1997. Bioactivation
of
leukotoxins to their toxic diols by epoxide hydrolase.
Nature Medicine 3(5):562-566.
368.
Hammock, B.D., D.H. Storms, and D.F. Grant.
1997.
Epoxide Hydrolases In:
Comprehensive Toxicology, (Guengerich, F.P., ed.)
Pergamon, Oxford. Vol.
3 Biotransformation, Chapter 18,
pp.283-305, Pergamon, Oxford.
369.
Zheng, J., C. Myung,
A.D. Jones, and B.D. Hammock. 1997. Evidence of quinone
metabolites of
naphthalene covalently bound to sulfur nucleophiles of proteins of
murine clara
cells after exposure to naphthalene. Chem.
Res. Toxicol. 10(9):1008-1014.
370.
Müller, F., M. Arand, H. Frank, A. Seidel, W.
Hinz, L. Winkler, K. Hänel,
E. Blée, J.K. Beetham, B.D. Hammock and F. Oesch.
1997.
Visualization of a covalent intermediate between
microsomal epoxide
hydrolase, but not cholesterol epoxide hydrolase, and their substrates. Eur. J. Biochem. 245:490-496.
371.
Hammock, B.D.
1997. Are
leukotoxins toxic? Nature
Medicine. 3(6):502.
378.
Zheng, J., G.T. Wurz, T.B. Cadman, M.W.
DeGregorio, A.D. Jones, and B.D. Hammock.
1997. Haloenol
lactone: A new
synergist of cancer chemotherapy in vitro.
Biochem. Biophys. Res. Commun. 241:13-17.
390.
Mitchell, A.E., J. Zheng, B.D. Hammock, M. Lo
Bello, and A.D. Jones. 1998. Structural and functional
consequences of
haloenol lactone inactivation of murine and human glutathione S-transferase.
Biochemistry.
37(19):6752-6759
391.
Pinot, F., E.D. Caldas, C. Schmidt, D.G.
Gilchrist, A.D. Jones, C.K. Winter and B.D. Hammock.
1997.
Characterization of epoxide hydrolase activity in Alternaria alternata f. sp. lycopersici.
Possible involvement in toxin
production. Mycopathologia 140(1):51-58.
392.
Debernard, S., C. Morisseau, T.F. Severson, L.
Feng, H. Wojtasek, G.D. Prestwich and B.D. Hammock.
1998.
Expression and characterization of the recombinant
juvenile hormone
epoxide hydrolase (JHEH) from Manduca
sexta. Insect
Biochem. Mol.
Biol. 28(5-6):409-419.
394.
Morisseau, C., G. Du, J.W. Newman and B.D.
Hammock. 1998. Mechanism of mammalian
soluble epoxide
hydrolase inhibition by chalcone oxide derivatives.
Arch. Biochem. Biophy.
356(2):214-228.
407.
Mullen, R.T., R.N. Trelease, H. Duerk, M.
Arand, B.D. Hammock, F. Oesch, and D.F. Grant.
(1999) Differential subcellular localization of endogenous
and
transfected soluble epoxide hydrolase in mammalian cells: Evidence for
isozyme
variants. FEBS Lett. 445(2-3):301-305.
410.
Morisseau, C., B.L. Ward, D.G. Gilchrist and
B.D. Hammock. 1999.
Multiple epoxide
hydrolases in Alternaria alternata
f.
sp. lycopersici and their
relationship to medium composition and host-specific toxin production. Appl. Environ. Microbiol. 65(6):2388-2395.
411.
Draper, A.J. and B.D. Hammock.
1999.
Soluble epoxide hydrolase in rat inflammatory cells is
indistinguishable
from soluble epoxide hydrolase in rat liver.
Toxicol. Sci. 50(1):30-35.
412.
Morisseau, C., M.H. Goodrow, D. Dowdy, J.
Zheng, J.F. Greene, J.R. Sanborn, and B.D. Hammock.
1999.
Potent urea and carbamate inhibitors of soluble epoxide
hydrolases. Proc.
Natl. Acad. Sci. USA 96(16):8849-8854.
415.
Argiriadi, M.A., C. Morisseau, B.D. Hammock
and D.W. Christianson. 1999. Detoxification of
environmental mutagens and
carcinogens: Structure, mechanism, and evolution of liver epoxide
hydrolase. Proc.
Natl. Acad. Sci.
USA 96(19):10637-10642.
416.
Draper, A.J. and B.D. Hammock.
1999. Inhibition of soluble and microsomal
epoxide hydrolase by zinc and other metals.
Toxicol. Sci. 52(1):26-32.
418.
Morisseau, C., M. Derbel, T.R. Lane, D.
Stoutamire and B.D. Hammock. 1999. Differential induction of
hepatic
drug-metabolizing enzymes by fenvaleric acid in male rats. Toxicol. Sci.
52(2):148-153.
419.
Lakritz, J., B.S. Winder, J. Noorouz-Zadeh,
T.L. Huang, A.R. Buckpitt, B.D. Hammock, and C.G. Plopper. 2000.
Hepatic and pulmonary enzyme activities in horses. Am. J. Vet. Res. 61(2):152-157.
420.
Greene, J.F. and B.D. Hammock.
1999.
Toxicity of linoleic acid metabolites, in:
Eicosanoids and Other Bioactive Lipids in Cancer,
Inflammation,
and Radiation Injury, 4. (Honn,
K.V.,
L.J. Marnett and S.K. Nigam, Eds.), pp. 471-477.
Advances in Experimental Medicine and
Biology, Vol. 469, Kluwer Academic/Plenum Publishers, New York, NY.
422.
Greene, J.F., J. Zheng, D.F. Grant and B.D.
Hammock. 2000. Cytotoxicity of
1,2-epoxynaphthalene is
correlated with protein binding and in
situ glutathione depletion in cytochrome P4501A1 expressing
Sf-21
cells. Toxicol. Sci. 53(2):352-360.
426.
Draper, A.J. and B.D. Hammock.
2000.
Identification of CYP2C9 as a human liver microsomal
linoleic acid
epoxygenase. Arch.
Biochem.
Biophys. 376(1):199-205.
427.
Greene, J.F., J.W. Newman, K.C. Williamson
and B.D. Hammock. 2000. Toxicity of epoxy fatty
acids and related
compounds to cells expressing human soluble epoxide hydrolase. Chem. Res. Toxicol. 13(4):217-226.
429.
Greene, J.F., K.C. Williamson, J.W. Newman,
C. Morisseau and B.D. Hammock.
2000. Metabolism
of monoepoxides
of methyl linoleate: Bioactivation and detoxification.
Arch. Biochem. Biophys.
376(2):420-432.
430.
Argiriadi, M.A., C. Morisseau, M.H. Goodrow,
D.L. Dowdy, B.D. Hammock and D.W. Christianson.
2000. Binding
of alkylurea
inhibitors to epoxide hydrolase implicates active site tyrosines in
substrate
activation. J.
Biol. Chem. 275(20):15265-15270.
431.
Morisseau, C., J.K. Beetham, F. Pinot, S.
Debernard, J.W. Newman and B.D. Hammock.
2000. Cress
and potato soluble
epoxide hydrolases: Purification, biochemical characterization, and
comparison
to mammalian enzymes. Arch.
Biochem.
Biophys. 378(2):321-332.
433.
Yamada, T., C. Morisseau, J.E. Maxwell, M.A.
Argiriadi, D.W. Christianson and B.D. Hammock.
2000. Biochemical evidence for the involvement of tyrosine
in epoxide
activation during the catalytic cycle of epoxide hydrolase. J. Biol. Chem.
275(30):23082-23088.
440.
Fanucchi, M.V., A.R. Buckpitt, M.E. Murphy,
D.H. Storms, B.D. Hammock and C.G. Plopper.
2000. Development
of phase II
xenobiotic metabolizing enzymes in differentiating murine Clara cells. Toxicol. Appl. Pharmacol. 168(3):253-267.
441.
Nakagawa, Y., C.E. Wheelock, C. Morisseau,
M.H. Goodrow, B.G. Hammock and B.D. Hammock.
2000. 3-D
QSAR analysis of
inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas,
arylureas, and their analogues.
Bioorganic Med. Chem.
8(11):2663-2673.
442.
Yu, Z., F. Xu, L.M. Huse, C. Morisseau, A.J. Draper,
J.W. Newman, C. Parker, L. Graham, M.M. Engler, B.D. Hammock, D.C.
Zeldin and
D.L. Kroetz. 2000. Soluble epoxide hydrolase
regulates
hydrolysis of vasoactive epoxyeicosatrienoic acids.
Circ. Res.
87(11):992-998.
446.
Newman, J.W., D.L. Denton, C. Morisseau, C.S.
Koger, C.E. Wheelock, D.E. Hinton and B.D. Hammock.
2001.
Evaluation of fish models of soluble epoxide hydrolase
inhibition. Environ
Health Persp. 109(1):61-66.
448.
Williamson, K.C., C. Morisseau, J.E. Maxwell
and B.D. Hammock. 2000. Regio- and
enantioselective hydrolysis of
phenyloxiranes catalyzed by soluble epoxide hydrolase.
Tetrahedron: Asymmetr. 11:4451-4462.
452.
Slim, R.,
B.D. Hammock, M. Toborek, L.W. Robertson, J.W. Newman, C.H.P.
Morisseau, B.A.
Watkins,V. Saraswathi and B. Hennig.
2001. The
role of methyl-linoleic
acid epoxide and diol metabolites in the amplified toxicity of linoleic
acid
and polychlorinated biphenyls to vascular endothelial cells. Toxicol. Appl. Pharmacol.
171:184-193.
455.
Morisseau, C., J.W. Newman, D.L. Dowdy, M.H.
Goodrow and B.D. Hammock. 2001. Inhibition of microsomal
epoxide hydrolases by
ureas, amides and amines. Chem.
Res.
Toxicol. 14(4):409-415.
457.
Fang, X.,
T.L. Kaduce, N.L. Weintraub, S. Harmon, L.M. Teesch, C. Morisseau, D.A.
Thompson, B.D. Hammock and A.A. Spector.
2001. Pathways
of epoxyeicosatrienoic
acid metabolism in endothelial cells: Implications for the vascular
effects of
soluble epoxide hydrolase inhibition.
J.
Biol. Chem. 276(18):14867-14874.
458.
Sisemore, M.F., J. Zheng, J.C. Yang, D.A.
Thompson, C.G. Plopper, G.A. Cortopassi, and B.D. Hammock. 2001.
Cellular characterization of leukotoxin diol-induced
mitochondrial
dysfunction. Arch.
Biochem. Biophys.
392(1):32-37.
460.
Newman, J.W.
and B.D. Hammock. 2001. Optimized thiol
derivatizing reagent for the
mass spectral analysis of disubstituted epoxy fatty acids. J. Chromatogr. A.
925:223-240.
469.
Zheng, J., C.G. Plopper, J. Lakritz, D.H.
Storms and B.D. Hammock. 2001. Leukotoxin-diol: A
putative toxic mediator
involved in acute respiratory distress syndrome.
Am. J. Respir. Cell Mol. Biol. 25:434-438.
472.
Watanabe, T.
and B.D. Hammock. 2001. Rapid determination of
soluble epoxide
hydrolase inhibitors in rat hepatic microsomes by high performance
liquid
chromatography with electrospray tandem mass spectrometry. Anal. Biochem. 299:227-234.
476.
Morisseau, C.
and B.D. Hammock. 2002. Epoxide Hydrolases. In: Wiley Encyclopedia of
Molecular Medicine,
(Creighton, T.E. ed.), pp. 1194-1197, John Wiley & Sons, Inc.,
New York,
NY.
478.
Imig, J.D.,
X. Zhao, J.H. Capdevila, C. Morisseau and B.D. Hammock.
2002.
Soluble epoxide hydrolase inhibition lowers arterial blood
pressure in
angiotensin II hypertension.
Hypertension 39(2):690-694.
480.
Davis, B.B.,
D.A Thompson, L.L. Howard, C. Morisseau, B.D. Hammock and R.H. Weiss. 2002.
Inhibitors of soluble epoxide hydrolase attenuate vascular
smooth muscle
cell proliferation. PNAS
99:2222-2227.
486.
Nagy, S.R.,
J.R. Sanborn, B.D. Hammock and M.S. Denison.
2002. Development
of a green
fluorescent protein-based cell bioassay for the rapid and inexpensive
detection
and characterization of Ah receptor agonists.
Toxicol. Sci. 65:200-210.
487.
Hennig, B.,
B.D. Hammock, R. Slim, M. Toborek, V. Saraswathi and L.W. Robertson. 2002.
PCB-induced oxidative stress in endothelial cells:
modulation by
nutrients. Int. J.
Hyg. Environ. Health
205:95-102.
488.
Morisseau,
C., M.H. Goodrow, J.W. Newman, C.E. Wheelock, D.L. Dowdy and B.D.
Hammock. 2002.
Structural refinement of inhibitors of urea based soluble
epoxide
hydrolases. Biochem.
Pharmacol.
63:1599-1608.
492.
Newman, J.W.,
T. Watanabe and B.D. Hammock. 2002. The simultaneous
quantification of cytochrome
P450 dependent linoleate and arachidonate metabolites in urine by
HPLC-MS/MS. J.
Lipid Res. 43:1563-1578.
495.
Fornage, M.,
C.A. Hinojos, B.W. Nurowska, E. Boerwinkle, B.D. Hammock, C.H.P.
Morisseau and
P.A Doris. 2002. Polymorphism in soluble
epoxide hydrolase and
blood pressure in spontaneously hypertensive rats.
Hypertension 40:485-490.
500.
Fang, X.,
N.L. Weintraub, C.L. Oltman, L.L. Stoll, T.L. Kaduce, S. Harmon, K.C.
Dellsperger, C. Morisseau, B.D. Hammock and A.A. Spector. 2002.
Human coronary endothelial cells convert 14,15-EET to a
biologically
active chain-shortened epoxide. Amer.
J.
Physiol. Heart Circ. Physiol. 283:H2306-H2314.
504.
Newman, J.W., C. Morisseau, T.R. Harris and
B.D. Hammock. 2003. The soluble epoxide
hydrolase encoded by
EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase
activity. PNAS
100:1558-1563.
511.
McElroy,
N.R., P.C. Jurs, C. Morisseau and B.D. Hammock.
2003. QSAR
and classification of
murine and human soluble epoxide hydroalse inhibition by urea-like
compounds. J. Med.
Chem. 46:1066-1080.
517.
Zhang, R.,
K-D. Kang, G. Shan and B.D. Hammock.
2003. Design,
synthesis and
evaluation of novel P450 fluorescent probes bearing
α-cyanoether. Tetrahedron
Letts. 44:4331-4334.
522.
Watanabe, T.,
C. Morisseau, J.W. Newman and B.D. Hammock.
2003. In
vitro metabolism of the
mammalian soluble epoxide hydrolase inhibitor,
1-cyclohexyl-3-dodecyl-urea. Drug Metab. Dispos. 31:846-853.
523.
Przybyla-Zawislak, B.D., P.K. Srivastava, J.
Vázquez-Matiás, H.W.
Mohrenweiser, J. Maxwell, B.D. Hammock, J.A. Bradbury, A. E.
Enayetalla, D.C. Zeldin
and D.F. Grant. 2003 Polymorphism in human
soluble epoxide
hydrolase. Mol.
Pharmacol. 64:482-490.
524. Koivunen,
M.E., C. Morisseau, J.W. Newman, W.R. Horwath and B.D. Hammock. 2003.
Purification
and characterization of a methylene urea-hydrolyzing enzyme from Rhizobium radiobacter (Agrobacterium
tumefaciens). Soil
Biol. Biochem. 35:1433-1442.
528. Taniai K.,
A.B. Inceoglu, K. Yukuhiro, B.D. Hammock.
2003. Characterization
and cDNA
cloning of a clofibrate-inducible microsomal epoxide hydrolase in Drosophila melanogaster.
Eur. J. Biochem. 270:4696-4705.
529
Viswanathan, S., B.D. Hammock, J.W. Newman, P. Meerarani,
M. Toborek,
and B. Hennig. 2003. Involvement of CYP 2C9 in
Mediating the
Proinflammatory Effects of Linoleic Acid in Vascular Endothelial Cells. J. Am. Coll. Nutr.
22(6):502-510
533. Chiappe,
C., E. Leandri, S. Lucchesi, D. Pieraccini, B.D. Hammock and C.
Morisseau. 2004.
Biocatalysis in ionic liquids: the stereoconvergent
hydrolysis of trans-ß-methylstyrene
oxide catalyzed by
soluble epoxide hydrolase. J.
Molec.
Catal. 27:243-248.
538. Yu, Z., B.B. Davis, C.
Morisseau, B.D.
Hammock, J.L. Olson, D.L. Kroetz and R.H. Weiss.
2004.
Vascular localization of soluble epoxide hydrolase in the
human kidney. Am.
J. Physiol.-Renal Physiol. 286:F720-F726.
539.
Koivunen, M.E.,
C. Morisseau, W.R. Horwath and B.D. Hammock.
2004. Isolation of a strain of Agrobacterium
tumefaciens (Rhizobium radiobacter) utilizing methylene urea (ureaformaldehyde) as
nitrogen source. Can.
J. Microbiol. 50:167-174.
540.
DuTeaux,
S.B., J.W. Newman, C.H. Morisseau, E.A. Fairbairn, K.A. Jelks, B.D.
Hammock and
M.G. Miller. 2004. Epoxide hydrolases in the
rat epididymis:
possible roles in xenobiotic and endogenous fatty acid metabolism. Toxicol. Sci.
78:187-195.
541.
Gomez, G.A.,
C. Morisseau, B.D. Hammock and D.W. Christianson.
2004.
Structure of human epoxide hydrolase reveals mechanistic
inferences on
bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochem.
43:4716-4723.
542.
Zhao, X., T. Yamamoto, J.W. Newman, I.H. Kim,
T. Watanabe, B.D. Hammock, J. Stewart, J.S. Pollock, D.M.
Pollock and J.D.
Imig. 2004. Soluble epoxide hydrolase
inhibition protects
the kidney from hypertension-induced damage.
J. Am. Soc. Nephrol.
15:1244-1253.
543.
Kim, I., C.
Morisseau, T. Watanabe and B.D. Hammock.
2004. Design,
synthesis, and
biological activity of 1,3-disubstituted ureas as potent inhibitors of
the
soluble epoxide hydrolase of increased water solubility. J. Med. Chem.
47:2110-2122.
545.
Stok, J.E.,
H. Huang, P.D. Jones, C.E. Wheelock, C. Morisseau and B.D. Hammock. 2004.
Identification, expression and purification of a
pyrethroid hydrolyzing
carboxylesterase from mouse liver microsomes.
J. Biol. Chem. 279:29863-29869.
548.
Seubert, J.,
B. Yang, J.A. Bradbury, J. Graves, L. M. Degraff, S. Gabel, R. Gooch,
J. Foley,
J. Newman, L. Mao, H.A. Rockman, B.D. Hammock, E. Murphy and D.C.
Zeldin. 2004.
Enhanced postischemic functional recovery in CYP2J2
transgenic hearts
involves mitochondrial ATP-sensitive K+ channels
and p42/44 MAPK
pathway. Circ. Res.
95:506-514.
551.
Dey, A., R.S.
Williams, D.M. Pollock, D.W. Stepp, J.W. Newman, B.D. Hammock and J.D.
Imig. 2004. Altered Kidney CYP2C and
Cylooxygenase-2
levels are associated with obesity-related albuminuria.
Obes. Res. 12:1278-1289.
552.
Dettmer, K. and B.D. Hammock.
2004.
Metabolomics—A new field within the
“omics” sciences.
Environ. Health Perspect.
112:A396-A397.
554.
Dettmer, K. and B.D. Hammock.
2004.
Metabolomics-Just another "omics" word?
G.I.T. Lab J.
8:29-30.
555.
Fang, X.,
N.L. Weintraub, R.B. McCaw, S. Hu, S.D. Harmon, J.B. Rice, B.D. Hammock
and
A.A. Spector. 2004. Effect of soluble epoxide
hydrolase
inhibition on epoxyeicosatrienoic acid metabolism in human blood
vessels. Am. J.
Physiol.-Heart C. 287:H2412-H2420.
557.
Newman, J.W., C. Morisseau and B.D.
Hammock. 2005. Epoxide hydrolases: Their roles and
interactions with lipid
metabolism. Prog.
Lipid Res. 44:1-51.
558.
Smith, K.R., K.E. Pinkerton, T. Watanabe,
T.L. Pedersen, S.J. Ma and B.D. Hammock.
2005. Attenuation
of tobacco
smoke-induced lung inflammation by treatment with a soluble epoxide
hydrolase
inhibitor. PNAS 102:2186-2191.
560.
Morisseau, C.
and B.D. Hammock. 2005. Epoxide hydrolases: mechanisms, inhibitor
designs, and biological
roles. Annu. Rev.
Pharmacol.
Toxicol. 45:311-333.
562.
Hennebold, J.D., K. Mah, W. Perez, J.E.
Vance, R.L. Stouffer, C. Morisseau, B.D. Hammock and E.Y. Adashi. 2005.
Identification and characterization of an ovary-selective
isoform of
epoxide hydrolase. Biol.
Reprod. 72:968-975.
563.
Huang, H., J.E. Stok, D.W. Stoutamire, S.J.
Gee and B.D. Hammock. 2005. Development of optically
pure pyrethroid-like
fluorescent substrates for carboxylesterases.
Chem. Res. Toxicol. 18:516-527.
564.
Jung, O., R.P.
Brandes, I. Kim, F. Schweda, R. Schmidt, B.D. Hammock, R. Busse and I.
Fleming. 2005. Soluble epoxide hydrolase
is a main effector
of angiotensin II-induced hypertension.
Hypertension. 45:759-765.
565.
Newman, J.W.,
J.E. Stok, J.D. Vidal, C.J. Corbin, Q. Huang, B.D. Hammock and A.J.
Conley. 2004. Cytochrome P450-dependent
lipid metabolism in
preovulatory follicles.
Endocrinology. 145:5097-5105.
571.
Sellers,
K.W., C. Sun, C. Diez-Freire, H. Waki, C. Morisseau, J.R. Falck, B.D.
Hammock,
J.F. Paton and M.K. Raizada. 2005. Novel mechanism of brain
soluble epoxide
hydrolase-mediated blood pressure regulation in the spontaneously
hypertensive
rat. FASEB J. 19:626-628.
576.
Kim, I.-H., F.R. Heirtzler, C. Morisseau, K.
Nishi, H.-J. Tsai and B.D. Hammock.
2005. Optimization
of amide-based
inhibitors of soluble epoxide hydrolase with improved water solubility. J. Med. Chem.
48:3621-3629.
577.
Aronov, P.A., K. Dettmer, J.A. Christiansen,
A.J. Cornel and B.D. Hammock. 2005. Development of a
HPLC/tandem-MS method for
the analysis of the larvicides methoprene, hydroprene and kinoprene at
trace
levels using Diels-Alder derivatization.
J. Agric. Food Chem.
53:3306-3312.
578
Nithipatikom, K., M.P. Endsley, M.A. Isbell,
C.E. Wheelock, B.D. Hammock and W.B. Campbell.
2005. A
new class of inhibitors
of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer. Biochem. Bioph. Res. Co. 332:1028-1033.
579.
Jones,
P.D., N.M. Wolf, C. Morisseau, P. Whetstone, B. Hock and B.D. Hammock. 2005.
Fluorescent
substrates for soluble epoxide hydrolase and application to inhibition
studies. Anal. Biochem.
343:66-75.
580.
Fang, X., S.
Hu, T. Watanabe, N.L. Weintraub, G.D. Snyder, J. Yao, Y. Liu, J. Y.-J.
Shyy,
B.D. Hammock and A.A. Spector.
2005. Activation
of peroxisome
proliferators-activated receptor a
by substituted
urea-derived soluble epoxide hydrolase
inhibitors. J.
Pharmacol. Exp.
Ther. 314:260-270.
581.
Schmelzer,
K.R., L. Kubala, J.W. Newman, I.-H. Kim, J.P. Eiserich and B.D. Hammock. 2005.
Soluble epoxide hydrolase is a therapeutic target for
acute
inflammation. PNAS. 102:9772-9777.
583.
Kang, K.-D., P.D. Jones, H. Huang, R. Zhang,
L.A. Mostovich, C.E. Wheelock, T. Watanabe, L.F. Gulyaeva and B.D.
Hammock. 2005. Evaluation of a-cyano
ethers as
fluorescent substrates for assay of cytochrome P450 enyzme activity. Anal. Biochem. 344:183-192.
584.
Wheelock, C.E., K. J. Eder, I. Werner, H.
Huang, P.D. Jones, B.F. Brammell, A.A. Elskus and B.D. Hammock. 2005.
Individual variability in esterase activity and CYP1A
levels in Chinook
salmon (Oncorhynchus tshawytscha)
exposed to esfenvalerate and chlorpyrifos.
Aquat. Toxicol. 74:172-192.
585.
German, J.B., B.D. Hammock and S.M. Watkins. 2005.
Metabolomics: building
on a
century of biochemistry to guide human health.
Metabolomics 1:3-9.
587.
Tran, K.L., P.A. Aronov, H. Tanaka, J.W.
Newman, B.D. Hammock and C. Morisseau.
2005. Lipid
sulfates and
sulfonates are allosteric competitive inhibitors of the N-terminal
phosphatase
activity of the mammalian soluble epoxide hydrolase.
Biochemistry-US. 44:12179-12187.
589.
Liu, Y., Y. Zhang, K. Schmelzer, T.-S. Lee,
X. Fang, Y. Zhu, A.A. Spector, S. Gill, C. Morisseau, B.D. Hammock and
J.Y-J.
Shyy. 2005. The anti-inflammatory
effect of laminar
flow: The role of
PPARγ, epoxyeicosatrienoic
acids, and soluble epoxide hydrolase.
PNAS. 102:16747-16752.
590.
Vriens, J., G. Owsianik, B. Fisslthaler, M.
Suzuki, A. Janssens, T. Voets, C. Morisseau, B.D. Hammock, I. Fleming,
R. Busse
and B. Nilius. 2005. Modulation of the Ca2+
permeable
cation channel TRPV4 by cytochrome P450 epoxygenases in vascular
endothelium. Circ.
Res. 97:908-915.
594.
Dorrance, A.M., N. Rupp, D.M. Pollock, J.W. Newman, B.D. Hammock and J.D.
Imig. 2005.
An epoxide hydrolase inhibitor,
12-(3-Adamantan-1-yl-ureido) dodecanoic
acid (AUDA) reduces ischemic cerebral infarct size in stroke-prone
spontaneously hypertensive rats.&nb